Dental pulp stem cells

被引：98

作者：

Liu, He ^{[1
]}

Gronthos, Stan

Shi, Songtao

机构：

[1] Peking Univ, Sch Stomatol, Beijing, Peoples R China

[2] Univ So Calif, Sch Dent, Ctr Craniofacial Mol Biol, Los Angeles, CA 90033 USA

来源：

ADULT STEM CELLS | 2006年 / 419卷

关键词：

D O I：

10.1016/S0076-6879(06)19005-9

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Postnatal stem cells have been isolated from a variety of tissues. These stem cells are thought to possess great therapeutic potential for repairing damaged and/or defective tissues. Clinically, hematopoietic stem cells have been successfully used for decades in the treatment of various diseases and disorders. However, the therapeutic potential of other postnatal stem cell populations has yet to be realized, because of the lack of detailed understanding of their stem cell characteristics at the cellular and molecular levels. Furthermore, there is limited knowledge of their therapeutic value at the preclinical level. Therefore, it is necessary to develop optimal strategies and approaches to overcome the substantial challenges currently faced by researchers examining the clinical efficacy of different postnatal stem cell populations. In this review, we introduce methodologies for isolating postnatal stem cells from human dental pulp and discuss their potential role in tissue regeneration.

引用

页码：99 / 113

页数：15

共 65 条

[1] Human dentin production in vitro [J].