Fabrication of carbohydrate chips for studying protein-carbohydrate interactions

被引：0
|
作者：
Park, SJ [1 ]
Shin, IJ [1 ]
机构：
[1] Yonsei Univ, Dept Chem, Seoul 120749, South Korea
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2002年 / 41卷 / 17期
关键词：
D O I：
10.1002/1521-3773(20020902)41:17<3180::AID-ANIE3180>3.0.CO;2-S
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new tool for the high-throughput study of carbohydrate-protein interactions: Maleimide-linked carbohydrates (e.g. 1) were immobilized on thiol-derivatized glass slides, and the microspots were probed with fluorescein-labeled lectins (see picture). The binding of lectins to the carbohydrates on the slide depends on the concentration of the immobilized carbohydrates and on the length of the tethers.
引用
收藏
页码：3180 / +
页数：4
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