Fabrication of carbohydrate chips for studying protein-carbohydrate interactions

被引：0
|
作者：
Park, SJ [1 ]
Shin, IJ [1 ]
机构：
[1] Yonsei Univ, Dept Chem, Seoul 120749, South Korea
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2002年 / 41卷 / 17期
关键词：
D O I：
10.1002/1521-3773(20020902)41:17<3180::AID-ANIE3180>3.0.CO;2-S
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new tool for the high-throughput study of carbohydrate-protein interactions: Maleimide-linked carbohydrates (e.g. 1) were immobilized on thiol-derivatized glass slides, and the microspots were probed with fluorescein-labeled lectins (see picture). The binding of lectins to the carbohydrates on the slide depends on the concentration of the immobilized carbohydrates and on the length of the tethers.
引用
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页码：3180 / +
页数：4
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