Construction of a fluorescent probe for selectively detecting singlet oxygen with a high sensitivity and large concentration range based on a two-step cascade sensing reaction

被引：25

作者：

Long, Lingliang ^{[1
]}

Yuan, Xiangqi ^{[1
]}

Cao, Siyu ^{[1
]}

Han, Yuanyuan ^{[1
]}

Liu, Weiguo ^{[1
]}

Chen, Qian ^{[1
]}

Gong, Aihua ^{[2
]}

Wang, Kun ^{[1
,3
]}

机构：

[1] Jiangsu Univ, Sch Chem & Chem Engn, Zhenjiang 212013, Jiangsu, Peoples R China

[2] Jiangsu Univ, Sch Med, Zhenjiang 212013, Jiangsu, Peoples R China

[3] Qingdao Univ Sci & Technol, Key Lab Opt Elect Sensing & Analyt Chem Lift Sci, Minist Educ, Coll Chem & Mol Engn, Qingdao 266042, Shandong, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 58期

基金：

中国国家自然科学基金;

关键词：

PHOTODYNAMIC THERAPY; HYDROGEN-PEROXIDE; GENERATION; MECHANISM; CANCER; DAMAGE;

D O I：

10.1039/c9cc04300d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel fluorescent probe XQ-1 for selectively detecting O-1(2) on the basis of a two-step cascade reaction has been rationally constructed. The probe responded to O-1(2) not only showing a high sensitivity, but also displaying a large concentration range, which means that the probe can be used as a powerful tool to monitor the efficacy of PDT toward cancer and concurrently track the adverse effects on healthy cells.

引用

页码：8462 / 8465

页数：4

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