Construction of a fluorescent probe for selectively detecting singlet oxygen with a high sensitivity and large concentration range based on a two-step cascade sensing reaction

被引：25
作者：
Long, Lingliang [1 ]
Yuan, Xiangqi [1 ]
Cao, Siyu [1 ]
Han, Yuanyuan [1 ]
Liu, Weiguo [1 ]
Chen, Qian [1 ]
Gong, Aihua [2 ]
Wang, Kun [1 ,3 ]
机构：
[1] Jiangsu Univ, Sch Chem & Chem Engn, Zhenjiang 212013, Jiangsu, Peoples R China
[2] Jiangsu Univ, Sch Med, Zhenjiang 212013, Jiangsu, Peoples R China
[3] Qingdao Univ Sci & Technol, Key Lab Opt Elect Sensing & Analyt Chem Lift Sci, Minist Educ, Coll Chem & Mol Engn, Qingdao 266042, Shandong, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 58期
基金：
中国国家自然科学基金;
关键词：
PHOTODYNAMIC THERAPY; HYDROGEN-PEROXIDE; GENERATION; MECHANISM; CANCER; DAMAGE;
D O I：
10.1039/c9cc04300d
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel fluorescent probe XQ-1 for selectively detecting O-1(2) on the basis of a two-step cascade reaction has been rationally constructed. The probe responded to O-1(2) not only showing a high sensitivity, but also displaying a large concentration range, which means that the probe can be used as a powerful tool to monitor the efficacy of PDT toward cancer and concurrently track the adverse effects on healthy cells.
引用
收藏
页码：8462 / 8465
页数：4
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