Clinical manifestations and factors associated with mortality from COVID-19 in older adults: Retrospective population-based study with 9807 older Brazilian COVID-19 patients

被引:28
作者
de Souza, Carlos D. F. [1 ]
de Arruda Magalhaes, Amanda J. [2 ]
Lima, Ayara J. P. D. [2 ]
Nunes, Danielle N. [2 ]
de Fatima Machado Soares, Erika [2 ]
de Castro Silva, Louryanne [2 ]
Santos, Lucas G. [2 ]
dos Santos Cardoso, Vitoria, I [2 ]
Nobre, Yasmin V. S. [2 ]
do Carmo, Rodrigo F. [3 ,4 ]
机构
[1] Fed Univ Alagoas UFAL, Postgrad Program Hlth Family, Dept Med, Arapiraca, Brazil
[2] Fed Univ Alagoas UFAL, Dept Med, Arapiraca, Brazil
[3] Fed Univ Vale Sao Francisco UNIVASF, Postgrad Program Hlth & Biol Sci, Petrolina, Brazil
[4] Fed Univ Vale Sao Francisco UNIVASF, Postgrad Program Biosci, Petrolina, Brazil
关键词
COVID-19; elderly; geriatric patients; mortality; risk factors;
D O I
10.1111/ggi.14061
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Aim Older adults are the main risk group for coronavirus disease 2019 (COVID-19). This study aimed to describe the clinical manifestations and factors associated with mortality from COVID-19 among older adults in Brazil. Methods A cross-sectional observational study was carried out with data from 9807 cases of COVID-19 among older adults in the state of Alagoas, Brazil. We determined the case fatality rate between age groups and clinical factors associated with mortality. Results A total of 52.5% (n = 5145) were women, and with an average age of 70.21 +/- 8.37 years. The fatality rate was 11.9%, with a higher rate in men (14.4%) compared with women (9.8%). The fatality rate increased with age. The most common manifestations were fever (n = 4926; 50.2%), cough (n = 5737; 58.5%), headache (n = 1980; 20.2%) and fatigue (n = 2022; 20.6%). The most prevalent comorbidities were diabetes (n = 1528; 5.6%), cardiovascular disease (n = 1528; 15.6%) and systemic arterial hypertension (n = 597; 6.1%). The factors associated with mortality were male sex (OR 1.54), age >= 75 years (OR 2.40), dyspnea (OR 2.92), diabetes (OR 2.33), hypertension (OR 1.53) and chronic kidney disease (OR 2.02). Conclusions The profile and the risk factors evidenced show the need to adopt mechanisms to protect the elderly population.
引用
收藏
页码:1177 / 1181
页数:5
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