Characterization of a Bacillus subtilis thermosensitive teichoic acid-deficient mutant:: Gene mnaA (yvyH) encodes the UDP-N-acetylglucosarnine 2-epimerase

被引:30
|
作者
Soldo, B [1 ]
Lazarevic, V [1 ]
Pooley, HM [1 ]
Karamata, D [1 ]
机构
[1] Inst Genet & Biol Microbiennes, CH-1005 Lausanne, Switzerland
关键词
D O I
10.1128/JB.184.15.4316-4320.2002
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The Bacillus subtilis thermosensitive mutant ts-21 bears two C-G-->T-A transitions in the mnaA gene. At the nonpermissive temperature it is characterized by coccoid cell morphology and reduced cell wall phosphate content. MnaA converts UDP-N-acetylglucosamine into UDP-N-acetylmannosamine,, a precursor of the teichoic acid linkage unit.
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页码:4316 / 4320
页数:5
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