The epidemiology of venous thromboembolism

被引:789
作者
Heit, John A. [1 ]
Spencer, Frederick A. [2 ]
White, Richard H. [3 ]
机构
[1] Mayo Clin, Div Cardiovasc Dis JAH, Rochester, MN 55905 USA
[2] McMaster Univ, Div Cardiol, FAS, Hamilton, ON, Canada
[3] Univ Calif Davis, Div Gen Internal Med RHW, Sacramento, CA 95616 USA
关键词
Venous thromboembolism; Pulmonary embolism; Deep vein thrombosis; Thrombophlebitis; Epidemiology; DEEP-VEIN THROMBOSIS; ORAL ANTICOAGULANT-THERAPY; HOSPITALIZED MEDICAL PATIENTS; OBSTRUCTIVE SLEEP-APNEA; PULMONARY-EMBOLISM; RISK-FACTORS; 1ST EPISODE; D-DIMER; NATIONWIDE FAMILY; RECURRENCE RISK;
D O I
10.1007/s11239-015-1311-6
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Venous thromboembolism (VTE) is categorized by the U.S. Surgeon General as a major public health problem. VTE is relatively common and associated with reduced survival and substantial health-care costs, and recurs frequently. VTE is a complex (multifactorial) disease, involving interactions between acquired or inherited predispositions to thrombosis and VTE risk factors, including increasing patient age and obesity, hospitalization for surgery or acute illness, nursing-home confinement, active cancer, trauma or fracture, immobility or leg paresis, superficial vein thrombosis, and, in women, pregnancy and puerperium, oral contraception, and hormone therapy. Although independent VTE risk factors and predictors of VTE recurrence have been identified, and effective primary and secondary prophylaxis is available, the occurrence of VTE seems to be relatively constant, or even increasing.
引用
收藏
页码:3 / 14
页数:12
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