Neurologic Complications of Diabetes

被引:15
作者
Charnogursky, Gerald A. [1 ]
Emanuele, Nicholas V. [1 ]
Emanuele, Mary Ann [1 ]
机构
[1] Loyola Univ, Med Ctr, Fahey Ctr, Div Endocrinol & Metab, Maywood, IL 60153 USA
关键词
Pathogenesis; Diabetic neuropathy; Painful peripheral neuropathy; Diabetic autonomic neuropathy; Diabetic cardiovascular neuropathy; Diabetic gastroparesis; Therapeutic treatment diabetic neuropathy; ALPHA-LIPOIC ACID; CARDIAC AUTONOMIC NEUROPATHY; HEART-RATE-VARIABILITY; CORNEAL CONFOCAL MICROSCOPY; GLYCATION END-PRODUCTS; DOUBLE-BLIND; PERIPHERAL NEUROPATHY; NATURAL-HISTORY; GLUCOSE CONTROL; RISK-FACTORS;
D O I
10.1007/s11910-014-0457-5
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Neuropathy as a complication of diabetes is common and presents in a wide variety of clinical scenarios. Often the work-up is one of exclusion tempered with monitoring the response of symptoms to treatment options. The collaboration of a neurologist is often crucial to determining the best course of action for the patient. This review will address proposed pathogenic mechanisms and potential therapeutic interventions, both pharmacologic and nonpharmacologic.
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页数:16
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共 150 条
[1]   Effect of Prior Intensive Insulin Treatment During the Diabetes Control and Complications Trial (DCCT) on Peripheral Neuropathy in Type 1 Diabetes During the Epidemiology of Diabetes Interventions and Complications (EDIC) Study [J].
Albers, James W. ;
Herman, William H. ;
Pop-Busui, Rodica ;
Feldman, Eva L. ;
Martin, Catherine L. ;
Cleary, Patricia A. ;
Waberski, Barbara H. ;
Lachin, John M. .
DIABETES CARE, 2010, 33 (05) :1090-1096
[2]   NONINVASIVE ASSESSMENT OF CARDIAC DIABETIC NEUROPATHY BY C-11 HYDROXYEPHEDRINE AND POSITRON EMISSION TOMOGRAPHY [J].
ALLMAN, KC ;
STEVENS, MJ ;
WIELAND, DM ;
HUTCHINS, GD ;
WOLFE, ER ;
GREENE, DA ;
SCHWAIGER, M .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1993, 22 (05) :1425-1432
[3]  
Aminoff M, 1996, NEUROLOGY, V46, P873
[5]   Circadian patterns of heart rate variability, fibrinolytic activity, and hemostatic factors in type I diabetes mellitus with cardiac autonomic neuropathy [J].
Aronson, D ;
Weinrauch, LA ;
D'Elia, JA ;
Tofler, GH ;
Burger, AJ .
AMERICAN JOURNAL OF CARDIOLOGY, 1999, 84 (04) :449-453
[6]   Power spectral analysis of heart rate variation in diabetic patients with neuropathic foot ulceration [J].
Aso, Y ;
Fujiwara, Y ;
Inukai, T ;
Takemura, Y .
DIABETES CARE, 1998, 21 (07) :1173-1177
[7]   Gabapentin for the symptomatic treatment of painful neuropathy in patients with diabetes mellitus - A randomized controlled trial [J].
Backonja, M ;
Beydoun, A ;
Edwards, KR ;
Schwartz, SL ;
Fonseca, V ;
Hes, M ;
LaMoreaux, L ;
Garofalo, E .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1998, 280 (21) :1831-1836
[8]   Gabapentin dosing for neuropathic pain: Evidence from randomized, placebo-controlled clinical trials [J].
Backonja, M ;
Glanzman, RL .
CLINICAL THERAPEUTICS, 2003, 25 (01) :81-104
[9]   NGX-4010, a high concentration capsaicin patch, for the treatment of postherpetic neuralgia: a randomised, double-blind study (vol 7, pg 1106, 2008) [J].
Backonja, M. ;
Wallace, M. S. ;
Blonsky, E. R. .
LANCET NEUROLOGY, 2009, 8 (01) :31-31
[10]  
BANNISTER R, 1988, AUTONOMIC FAILURE TX, P569