Interferon-induced vitiligo in a patient with chronic viral hepatitis C infection

被引：49
作者：
Simsek, H
Savas, C
Akkiz, H
Telatar, H
机构：
[1] Hacettepe University Medical School, Department of Internal Medicine, Section of Gastroenterology, Ankara
来源：
DERMATOLOGY | 1996年 / 193卷 / 01期
关键词：
interferons; chronic hepatitis C; vitiligo;
D O I：
10.1159/000246208
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Vitiligo is an autoimmune disease characterized by depigmentation of the skin due to destruction of melanocytes. Interferons have been used for the treatment of chronic hepatitis C and some malignancies. We report interferon alpha-2a-induced vitiligo in a male patient with chronic active hepatitis C. All skin lesions disappeared completely without requiring therapy after discontinuation of interferon. This case suggests that vitiligo may be developed during interferon therapy as a side effect.
引用
收藏
页码：65 / 66
页数：2
相关论文
共 11 条
[1]   FURTHER EVIDENCE FOR INVOLVEMENT OF BOTH CELL-MEDIATED AND HUMORAL IMMUNITY IN GENERALIZED VITILIGO [J].
ABDELNASER, MB ;
KRUGERKRASAGAKES, S ;
KRASAGAKIS, K ;
GOLLNICK, H ;
ORFANOS, CE .
PIGMENT CELL RESEARCH, 1994, 7 (01) :1-8
[2]  
BERNSTEIN D, 1995, AM J GASTROENTEROL, V90, P1176
[3]   INTERFERON-INDUCED PSORIASIS IN A PATIENT WITH CHRONIC HEPATITIS-C [J].
GARCIALORA, E ;
TERCEDOR, J ;
MASSARE, E ;
LOPEZNEVOT, MA ;
SKILJO, M ;
GARCIAMELLADO, V .
DERMATOLOGY, 1993, 187 (04) :280-280
[4]   THERAPY OF DISSEMINATED MALIGNANT-MELANOMA WITH RECOMBINANT INTERFERON-ALPHA-2B AND PIROXICAM - CLINICAL-RESULTS WITH A REPORT OF AN UNUSUAL RESPONSE-ASSOCIATED FEATURE (VITILIGO) AND UNUSUAL TOXICITY (DIFFUSE PULMONARY INTERSTITIAL FIBROSIS) [J].
HARRIS, J ;
BINES, S ;
DASGUPTA, T .
MEDICAL AND PEDIATRIC ONCOLOGY, 1994, 22 (02) :103-106
[5]   AUTOIMMUNITY IN VITILIGO - RELATIONSHIP WITH HLA, GM AND KM POLYMORPHISMS [J].
LORINI, R ;
ORECCHIA, G ;
MARTINETTI, M ;
DUGOUJON, JM ;
CUCCIA, M .
AUTOIMMUNITY, 1992, 11 (04) :255-260
[6]   ANTIBODIES TO NORMAL HUMAN MELANOCYTES IN VITILIGO [J].
NAUGHTON, GK ;
EISINGER, M ;
BYSTRYN, JC .
JOURNAL OF EXPERIMENTAL MEDICINE, 1983, 158 (01) :246-251
[7]   VITILIGO - WHERE DO WE STAND [J].
ORTONNE, JP ;
BOSE, SK .
PIGMENT CELL RESEARCH, 1993, 6 (02) :61-72
[8]  
PRIMO J, 1993, AM J GASTROENTEROL, V88, P1976
[9]   VITILIGO AND OTHER DISEASES - COEXISTENCE OR TRUE ASSOCIATION - HAMBURG STUDY ON 321 PATIENTS [J].
SCHALLREUTER, KU ;
LEMKE, R ;
BRANDT, O ;
SCHWARTZ, R ;
WESTHOFEN, M ;
MONTZ, R ;
BERGER, J .
DERMATOLOGY, 1994, 188 (04) :269-275
[10]  
SIMSEK H, IN PRESS NEPHROL DIA
12