Nanotechnologies for biomedical science and translational medicine

被引:70
作者
Heath, James R. [1 ]
机构
[1] CALTECH, Div Chem & Chem Engn, Pasadena, CA 91125 USA
关键词
nanotechnology; biotechnology; nanomedicine; SINGLE-CELL ANALYSIS; SEMICONDUCTOR QUANTUM DOTS; IN-VITRO DIAGNOSTICS; GOLD NANOPARTICLES; TUMOR-CELLS; BIOLOGICAL APPLICATIONS; MAGNETIC NANOPARTICLES; CANCER-IMMUNOTHERAPY; SIGNALING PATHWAYS; CARBON NANOTUBES;
D O I
10.1073/pnas.1515202112
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
In 2000 the United States launched the National Nanotechnology Initiative and, along with it, a well-defined set of goals for nanomedicine. This Perspective looks back at the progress made toward those goals, within the context of the changing landscape in biomedicine that has occurred over the past 15 years, and considers advances that are likely to occur during the next decade. In particular, nanotechnologies for health-related genomics and single-cell biology, inorganic and organic nanoparticles for biomedicine, and wearable nanotechnologies for wellness monitoring are briefly covered.
引用
收藏
页码:14436 / 14443
页数:8
相关论文
共 125 条
  • [21] Corbyn Zoe., 2015, The Guardian
  • [22] Cancer Immunotherapy
    Couzin-Frankel, Jennifer
    [J]. SCIENCE, 2013, 342 (6165) : 1432 - 1433
  • [23] Common pitfalls in nanotechnology: lessons learned from NCI's Nanotechnology Characterization Laboratory
    Crist, Rachael M.
    Grossman, Jennifer Hall
    Patri, Anil K.
    Stern, Stephan T.
    Dobrovolskaia, Marina A.
    Adiseshaiah, Pavan P.
    Clogston, Jeffrey D.
    McNeil, Scott E.
    [J]. INTEGRATIVE BIOLOGY, 2013, 5 (01) : 66 - 73
  • [24] Nanowire nanosensors for highly sensitive and selective detection of biological and chemical species
    Cui, Y
    Wei, QQ
    Park, HK
    Lieber, CM
    [J]. SCIENCE, 2001, 293 (5533) : 1289 - 1292
  • [25] Single-cell dissection of transcriptional heterogeneity in human colon tumors
    Dalerba, Piero
    Kalisky, Tomer
    Sahoo, Debashis
    Rajendran, Pradeep S.
    Rothenberg, Michael E.
    Leyrat, Anne A.
    Sim, Sopheak
    Okamoto, Jennifer
    Johnston, Darius M.
    Qian, Dalong
    Zabala, Maider
    Bueno, Janet
    Neff, Norma F.
    Wang, Jianbin
    Shelton, Andrew A.
    Visser, Brendan
    Hisamori, Shigeo
    Shimono, Yohei
    van de Wetering, Marc
    Clevers, Hans
    Clarke, Michael F.
    Quake, Stephen R.
    [J]. NATURE BIOTECHNOLOGY, 2011, 29 (12) : 1120 - U11
  • [26] Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
    Davis, Mark E.
    Zuckerman, Jonathan E.
    Choi, Chung Hang J.
    Seligson, David
    Tolcher, Anthony
    Alabi, Christopher A.
    Yen, Yun
    Heidel, Jeremy D.
    Ribas, Antoni
    [J]. NATURE, 2010, 464 (7291) : 1067 - U140
  • [27] A Quantitative Comparison of Single-Cell Whole Genome Amplification Methods
    de Bourcy, Charles F. A.
    De Vlaminck, Iwijn
    Kanbar, Jad N.
    Wang, Jianbin
    Gawad, Charles
    Quake, Stephen R.
    [J]. PLOS ONE, 2014, 9 (08):
  • [28] The golden age: gold nanoparticles for biomedicine
    Dreaden, Erik C.
    Alkilany, Alaaldin M.
    Huang, Xiaohua
    Murphy, Catherine J.
    El-Sayed, Mostafa A.
    [J]. CHEMICAL SOCIETY REVIEWS, 2012, 41 (07) : 2740 - 2779
  • [29] Gold nanoparticles in biomedical applications: recent advances and perspectives
    Dykman, Lev
    Khlebtsov, Nikolai
    [J]. CHEMICAL SOCIETY REVIEWS, 2012, 41 (06) : 2256 - 2282
  • [30] Controlled encapsulation of single-cells into monodisperse picolitre drops
    Edd, Jon F.
    Di Carlo, Dino
    Humphry, Katherine J.
    Koster, Sarah
    Irimia, Daniel
    Weitz, David A.
    Toner, Mehmet
    [J]. LAB ON A CHIP, 2008, 8 (08) : 1262 - 1264