The Synthesis of 4-(3,3-Dimethyl-3H-pyrrolo[2,3-f]quinolin-2-yl)pyrazoles and 4-(3,3-Dimethyl-3H-pyrrolo[3,2-h]quinolin-2-yl)pyrazoles

被引：18
|
作者：
Rashidi, A. [1 ]
Afghan, A. [1 ]
Baradarani, Mehdi M. [1 ]
Joule, John A. [2 ]
机构：
[1] Univ Urmia, Dept Chem, Fac Sci, Orumiyeh 57135, Iran
[2] Univ Manchester, Sch Chem, Manchester M13 9PL, Lancs, England
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2009年 / 46卷 / 03期
关键词：
DERIVATIVES;
D O I：
10.1002/jhet.18
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
5-Hydrazinoquinoline and 8-hydrazinoquinoline were converted via Fischer syntheses with 3-methylbutan-2-one into pyrido-indolenines 2,3,3-trimethyl-3H-pyrrolo[2,3-f]quinoline 7 and 2,3,3-trimethyl-3H-pyrrolo[3,2-h]quinoline 11, respectively. Exposure of the indolenines to the Vilsmeier reagent produced aminomethylene-malondialdehydes 8 and 12, which reacted with hydrazine or arylhydrazines to give 4(3H-pyrrolo[2,3-f]quinolin-2-yl)- and 4-(3H-pyrrolo[3,2-h]quinolin-2-yl)-pyrazoles, 9 and 13.
引用
收藏
页码：428 / 431
页数：4
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