Near-Infrared Thienoisoindigos with Aggregation-Induced Emission: Molecular Design, Optical Performance, and Bioimaging Application

被引：33

作者：

Chen, Weijie ^{[1
,2
,3
,4
]}

Zhang, Chen ^{[5
]}

Chen, Huijuan ^{[1
,2
,3
,4
]}

Zang, Kun ^{[5
]}

Liu, Sheng Hua ^{[1
,2
,3
,4
]}

Xie, Yuan ^{[6
]}

Tan, Ying ^{[5
]}

Yin, Jun ^{[1
,2
,3
,4
,6
,7
]}

机构：

[1] Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Minist Educ, Wuhan 430079, Peoples R China

[2] Cent China Normal Univ, Hubei Int Sci & Technol Cooperat Base Pesticide &, Wuhan, Peoples R China

[3] Cent China Normal Univ, Int Joint Res Ctr Intelligent Biosensing Technol, Wuhan 430079, Peoples R China

[4] Cent China Normal Univ, Coll Chem, Wuhan 430079, Peoples R China

[5] Tsinghua Univ, Grad Sch Shenzhen, State Key Lab Chem Oncogen, Key Lab Chem Biol, Shenzhen 518055, Guangdong, Peoples R China

[6] Guangdong Prov Key Lab Radioact & Rare Resource U, Shaoguan 512026, Peoples R China

[7] Hubei Univ, Minist Educ Key Lab Synth & Applicat Organ Funct, Wuhan 430062, Peoples R China

来源：

ANALYTICAL CHEMISTRY | 2021年 / 93卷 / 07期

基金：

中国国家自然科学基金;

关键词：

FLUORESCENT-PROBES; AIE LUMINOGENS; DYE; BEHAVIOR; MECHANOCHROMISM; CONSTRUCTION; ENHANCEMENT; PROGRESS;

D O I：

10.1021/acs.analchem.0c04260

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Thienoisoindigo as a popular conjugated skeleton has been constantly applied in the construction of organic optoelectronic materials. Exploring its new applications in fluorescent sensors and bioimaging is helpful to extend its potential. In this work, a thienoisoindigo fluorophore was first selected as a building block to be applied in the construction of the near-infrared fluorescent materials with an aggregation-induced emission manner through introducing triarylamine, thiophene-bridged triarylamine, and N,N-dimethyl styrene, respectively. These fluorescent agents showed the near-infrared emission and possessed typical aggregation-induced emission behavior. Although they had low band gaps and near-infrared emission, they presented remarkable photostability. Especially, thiophene-bridged triarylamine and N,N-dimethyl styrene-coated thienoisoindigos exhibited strong lysosomal targeting capability, and they could also serve for fluorescence imaging in vivo.

引用

页码：3378 / 3385

页数：8

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