Aims To investigate association between leisure-time physical activity at weekends and the risk of developing Type 2 diabetes mellitus (DM). Methods Prospective examination of 6013 Japanese men aged 35-60 years who were free of DM, impaired fasting glycaemia, or hypertension at study entry. Type 2 DM was defined by a fasting plasma glucose level greater than or equal to 7.0 mmol/l or a 2-h post-load plasma glucose level greater than or equal to 11.1 mmol/l. Data on physical activity obtained from questionnaires consisted of overall leisure-time physical activity weekly and leisure-time physical activity at weekends. Results During the 59 966 person-years follow-up, 444 cases developed Type 2 DM. Regular physical exercise at least once a week was associated with a reduced risk of Type 2 DM. After adjustments for age, body mass index, daily alcohol consumption, smoking habits, blood pressure levels and a parental history of Type 2 DM, men who engaged in regular physical exercise at least once a week had a relative risk of Type 2 DM of 0.75 (95% CI, 0.61-0.93) compared with men engaging in exercise less often. Even vigorous activity only once a week at weekends was associated with a reduced risk of Type 2 DM. Men who engaged in vigorous activity at least once a week at weekends had a multiple-adjusted relative risk of Type 2 DM of 0.55 (95% CI, 0.35-0.88) compared with sedentary men. Conclusions Regular physical exercise at least once a week and vigorous activity even only once a week at weekends are associated with a decreased risk of Type 2 DM.
机构:
Hitachi Ltd, Hitachi Hlth Care Ctr, Hitachi, Ibaraki, JapanHitachi Ltd, Hitachi Hlth Care Ctr, Hitachi, Ibaraki, Japan
Honda, Toru
Kuwahara, Keisuke
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Natl Ctr Global Hlth & Med, Ctr Clin Sci, Dept Epidemiol & Prevent, Shinjuku Ku, Tokyo, Japan
Teikyo Univ, Grad Sch Publ Hlth, Itabashi Ku, Tokyo, JapanHitachi Ltd, Hitachi Hlth Care Ctr, Hitachi, Ibaraki, Japan
Kuwahara, Keisuke
Nakagawa, Tohru
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Hitachi Ltd, Hitachi Hlth Care Ctr, Hitachi, Ibaraki, JapanHitachi Ltd, Hitachi Hlth Care Ctr, Hitachi, Ibaraki, Japan
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Emory Univ, Sch Med, Dept Family & Prevent Med, Atlanta, GA 30322 USA
Emory Univ, Emory Global Diabet Res Ctr, Woodruff Hlth Sci Ctr, Atlanta, GA USAEmory Univ, Sch Med, Dept Family & Prevent Med, Atlanta, GA 30322 USA
Thirunavukkarasu, Sathish
El Fil, Farah
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Univ Nicosia, Med Sch, Dept Med, Nicosia, CyprusEmory Univ, Sch Med, Dept Family & Prevent Med, Atlanta, GA 30322 USA
El Fil, Farah
Prokou, Maria
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Univ Nicosia, Med Sch, Dept Med, Nicosia, CyprusEmory Univ, Sch Med, Dept Family & Prevent Med, Atlanta, GA 30322 USA
Prokou, Maria
Venkatachalam, Aravind
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Emory Univ, Oxford Coll, Atlanta, GA USAEmory Univ, Sch Med, Dept Family & Prevent Med, Atlanta, GA 30322 USA
Venkatachalam, Aravind
Kumar, Siya
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Georgia Inst Technol, Coll Sci, Atlanta, GA USAEmory Univ, Sch Med, Dept Family & Prevent Med, Atlanta, GA 30322 USA
Kumar, Siya
Shifaly, Fathimath
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McMaster Univ, Populat Hlth Res Inst, Dept Global Hlth, Hamilton, ON, CanadaEmory Univ, Sch Med, Dept Family & Prevent Med, Atlanta, GA 30322 USA
Shifaly, Fathimath
Oldenburg, Brian
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La Trobe Univ, Baker Heart & Diabet Inst, Melbourne, Vic, Australia
La Trobe Univ, Sch Psychol & Publ Hlth, Melbourne, Vic, AustraliaEmory Univ, Sch Med, Dept Family & Prevent Med, Atlanta, GA 30322 USA
机构:
Shree Guru Gobind Singh Tricentenary Univ, Fac Physiotherapy, Gumgram, Haryana, IndiaShree Guru Gobind Singh Tricentenary Univ, Fac Physiotherapy, Gumgram, Haryana, India
Bhati, Pooja
Hussain, M. Ejaz
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Shree Guru Gobind Singh Tricentenary Univ, Fac Allied Hlth Sci & Physiotherapy, Gurugram, Haryana, IndiaShree Guru Gobind Singh Tricentenary Univ, Fac Physiotherapy, Gumgram, Haryana, India
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Waseda Univ, Fac Sport Sci, Tokorozawa, Saitama, Japan
Natl Ctr Global Hlth & Med, Dept Epidemiol & Prevent, Ctr Clin Sci, Tokyo, JapanWaseda Univ, Fac Sport Sci, Tokorozawa, Saitama, Japan
Kawakami, Ryoko
Kashino, Ikuko
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Natl Ctr Global Hlth & Med, Dept Epidemiol & Prevent, Ctr Clin Sci, Tokyo, JapanWaseda Univ, Fac Sport Sci, Tokorozawa, Saitama, Japan
Kashino, Ikuko
Kasai, Hiroshi
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Univ Occupat & Environm Hlth, Inst Ind Ecol Sci, Dept Environm Oncol, Fukuoka, Fukuoka, JapanWaseda Univ, Fac Sport Sci, Tokorozawa, Saitama, Japan
Kasai, Hiroshi
Kawai, Kazuaki
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Univ Occupat & Environm Hlth, Inst Ind Ecol Sci, Dept Environm Oncol, Fukuoka, Fukuoka, JapanWaseda Univ, Fac Sport Sci, Tokorozawa, Saitama, Japan
Kawai, Kazuaki
Li, Yun-Shan
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Univ Occupat & Environm Hlth, Inst Ind Ecol Sci, Dept Environm Oncol, Fukuoka, Fukuoka, JapanWaseda Univ, Fac Sport Sci, Tokorozawa, Saitama, Japan
Li, Yun-Shan
Nanri, Akiko
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Natl Ctr Global Hlth & Med, Dept Epidemiol & Prevent, Ctr Clin Sci, Tokyo, Japan
Fukuoka Womens Univ, Int Coll Arts & Sci, Dept Food & Hlth Sci, Fukuoka, Fukuoka, JapanWaseda Univ, Fac Sport Sci, Tokorozawa, Saitama, Japan
Nanri, Akiko
Higuchi, Mitsuru
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Waseda Univ, Fac Sport Sci, Tokorozawa, Saitama, JapanWaseda Univ, Fac Sport Sci, Tokorozawa, Saitama, Japan
Higuchi, Mitsuru
Mizoue, Tetsuya
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Natl Ctr Global Hlth & Med, Dept Epidemiol & Prevent, Ctr Clin Sci, Tokyo, JapanWaseda Univ, Fac Sport Sci, Tokorozawa, Saitama, Japan