Top value platform chemicals: bio-based production of organic acids

被引：220

作者：

Becker, Judith ^{[1
]}

Lange, Anna ^{[1
]}

Fabarius, Jonathan ^{[1
]}

Wittmann, Christoph ^{[1
]}

机构：

[1] Univ Saarland, Inst Syst Biotechnol, Saarbrucken, Germany

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 2015年 / 36卷

关键词：

RECOMBINANT ESCHERICHIA-COLI; SUCCINIC ACID; SACCHAROMYCES-CEREVISIAE; 3-HYDROXYPROPIONIC ACID; CORYNEBACTERIUM-GLUTAMICUM; BIOTECHNOLOGICAL PRODUCTION; GLYCOLIC ACID; ADIPIC ACID; BASFIA-SUCCINICIPRODUCENS; FERMENTATIVE PRODUCTION;

D O I：

10.1016/j.copbio.2015.08.022

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Driven by the quest for sustainability, recent years have seen a tremendous progress in bio-based production routes from renewable raw materials to commercial goods. Particularly, the production of organic acids has crystallized as a competitive and fast-evolving field, related to the broad applicability of organic acids for direct use, as polymer building blocks, and as commodity chemicals. Here, we review recent advances in metabolic engineering and industrial market scenarios with focus on organic acids as top value products from biomass, accessible through fermentation and biotransformation.

引用

页码：168 / 175

页数：8

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