An easy purification of glycoluril clips by affinity chromatography

被引:0
作者
Golari, Neda [1 ]
Rahimizadeh, Mohammad [1 ]
Bakavoli, Mehdi [1 ]
Rezaei-Seresht, Esmail [2 ]
机构
[1] Ferdowsi Univ Mashhad, Sch Sci, Dept Chem, Mashhad 913751436, Iran
[2] Hakim Sabzevari Univ, Sch Sci, Dept Chem, Sabzevar 9617976487, Iran
关键词
Merrifield resin; Molecular clip; Affinity chromatography; Purification; BINDING FEATURES;
D O I
10.1007/s10847-014-0414-6
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A convenient method for separation and purification of glycoluril clips was developed on the basis of affinity chromatography using a resorcinol-functionalized Merrifield resin. The modified resin was readily prepared via immobilization of phlroglucinol on Merrifield resin. It was used for successful isolation of the desired clip products from their corresponding reaction mixtures. Also, the resin could be repeatedly recycled and reused without any noticeable decrease in its effectiveness.
引用
收藏
页码:353 / 358
页数:6
相关论文
共 14 条
[1]   Reversible and covalent binding of drugs to human serum albumin: Methodological approaches and physiological relevance [J].
Bertucci, C ;
Domenici, E .
CURRENT MEDICINAL CHEMISTRY, 2002, 9 (15) :1463-1481
[2]  
Bom A, 2002, ANGEW CHEM INT EDIT, V41, P266
[3]   Hierarchical self-assembly of amphiphilic metallohosts to give discrete nanostructures [J].
Elemans, JAAW ;
Rowan, AE ;
Nolte, RJM .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (07) :1532-1540
[4]   Synthesis and physical properties of novel guanidine containing molecular clips. Strong host-guest binding and formation of a lyotropic liquid crystalline phase [J].
Gieling, GTW ;
Scheeren, HW ;
Israel, R ;
Nolte, RJM .
CHEMICAL COMMUNICATIONS, 1996, (02) :241-243
[5]  
Madrigal Domingo, 2006, J. Mex. Chem. Soc, V50, P175
[6]   Binding features of molecular clips. Separation of the effects of hydrogen bonding and pi-pi interactions [J].
Reek, JNH ;
Priem, AH ;
Engelkamp, H ;
Rowan, AE ;
Elemans, JAAW ;
Nolte, RJM .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (42) :9956-9964
[7]   Molecular and supramolecular objects from glycoluril [J].
Rowan, AE ;
Elemans, JAAW ;
Nolte, RJM .
ACCOUNTS OF CHEMICAL RESEARCH, 1999, 32 (12) :995-1006
[8]   Facile purification of rare cucurbiturils by affinity chromatography [J].
Sasmal, S ;
Sinha, MK ;
Keinan, E .
ORGANIC LETTERS, 2004, 6 (08) :1225-1228
[9]   BINDING FEATURES OF MOLECULAR CLIPS DERIVED FROM DIPHENYLGLYCOLURIL [J].
SIJBESMA, RP ;
KENTGENS, APM ;
LUTZ, ETG ;
VANDERMAAS, JH ;
NOLTE, RJM .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (20) :8999-9005
[10]   BINDING OF DIHYDROXYBENZENES IN A SYNTHETIC MOLECULAR CLIP - EFFECT OF HYDROGEN-BONDING AND PI-STACKING [J].
SIJBESMA, RP ;
KENTGENS, APM ;
NOLTE, RJM .
JOURNAL OF ORGANIC CHEMISTRY, 1991, 56 (10) :3199-3201