Fabrication and characterization of porous 3D whisker-covered calcium phosphate scaffolds

被引：27

作者：

Ye, Xingjiang ^{[1
]}

Zhou, Changchun ^{[1
]}

Xiao, Zhanwen ^{[1
]}

Fan, Yujiang ^{[1
]}

Zhu, Xiangdong ^{[1
]}

Sun, Yong ^{[1
]}

Zhang, Xingdong ^{[1
]}

机构：

[1] Sichuan Univ, Natl Engn Res Ctr Biomat, Chengdu 610064, Peoples R China

来源：

MATERIALS LETTERS | 2014年 / 128卷

基金：

中国国家自然科学基金;

关键词：

Calcium phosphate; Hydrothermal treatment; Porous structures; 3D whiskers; Bone tissue engineering; HYDROXYAPATITE WHISKERS; TCP; HA; COMPOSITE; CERAMICS;

D O I：

10.1016/j.matlet.2014.04.142

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Porous three-dimensional (3D) whisker-covered calcium phosphate (CaP) scaffolds were fabricated using a hydrothermal method. Porous CaP ceramics were first prepared by applying the H2O2 foaming method to mimic the porous structure of bones. Then, three-dimensional (3D) hydroxyapatite (Ca-10(PO4)(6)(OH)(2), HAp) micro-whiskers were generated in CaP ceramics by hydrothermal treatment. Scanning electronic microscopy (SEM) images revealed that the scaffolds maintained their porous structures and newly generated micro-whiskers with 3D morphologies were vertically grown on ceramic inner walls. Energy dispersive X-ray (EDX) and X-ray diffraction (XRD) confirmed that the micro-whiskers are made of HAp microcrystals. The HAp whisker formation mechanism was proposed. 3D HAP whisker-covered porous CaP ceramics provide a structural design reference for bone tissue engineering. (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：179 / 182

页数：4

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