The microstructure and swelling properties of laminated HAp/CS hydrogels

被引:0
作者
Zuo Guifu [1 ]
Lun Huidong [2 ]
Gao Guijing [2 ]
Song Yuhua [1 ]
机构
[1] Hebei United Univ, Coll Mat Sci & Engn, Hebei Prov Key Lab Inorgan Nonmetall Mat, Tangshan 063009, Hebei, Peoples R China
[2] Comp Engn & Technique Res Ctr Tangshan, Tangshan 063700, Peoples R China
来源
ADVANCED ENGINEERING MATERIALS III, PTS 1-3 | 2013年 / 750-752卷
基金
中国国家自然科学基金;
关键词
hydroxyapatite; chitosan; swelling; DRUG-RELEASE; MONTMORILLONITE; NANOCOMPOSITES; BEHAVIOR;
D O I
10.4028/www.scientific.net/AMR.750-752.1635
中图分类号
TQ174 [陶瓷工业]; TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Lamellar inorganic materials such as MMT and LDH are expected to improve swelling-deswelling behavior and fatigue property of CS. In this study, laminated hydroxyapatite (HAp)/ chitosan (CS) composite hydrogels with different HAp contents (0, 1%, 2%, 3%) were prepared by means of solution intercalation in this paper. Swelling/deswelling test indicates that 3HAp/CS hydrogel shows the best swelling/deswelling property which is ideal for large drug loading and slow drug release. The intercalated strucure of 3HAp/CS hydrogel was confirmed by TEM investigation.
引用
收藏
页码:1635 / +
页数:2
相关论文
共 8 条
  • [1] Cell proliferation and controlled drug release studies of nanohybrids based on chitosan-g-lactic acid and montmorillonite
    Depan, Dilip
    Kumar, Annamalai Pratheep
    Singh, Raj Pal
    [J]. ACTA BIOMATERIALIA, 2009, 5 (01) : 93 - 100
  • [2] He Liumin, 2011, Recent Pat Drug Deliv Formul, V5, P265
  • [3] Biomimetic apatite-coated alginate/chitosan microparticles as osteogenic protein carriers
    Lee, Min
    Li, Weimin
    Siu, Ronald K.
    Whang, Julie
    Zhang, Xinli
    Soo, Chia
    Ting, Kang
    Wu, Benjamin M.
    [J]. BIOMATERIALS, 2009, 30 (30) : 6094 - 6101
  • [4] Drug release behavior of chitosan-montmorillonite nanocomposite hydrogels following electro stimulation
    Liu, Kun-Ho
    Liu, Ting-Yu
    Chen, San-Yuan
    Liu, Dean-Mo
    [J]. ACTA BIOMATERIALIA, 2008, 4 (04) : 1038 - 1045
  • [5] Effect of clay content on electrostimulus deformation. and volume recovery behavior of a clay-chitosan hybrid composite
    Liu, Kun-Ho
    Liu, Ting-Yu
    Chen, San-Yuan
    Liu, Dean-Mo
    [J]. ACTA BIOMATERIALIA, 2007, 3 (06) : 919 - 926
  • [6] Biopolymer chitosan/montmorillonite nanocomposites: Preparation and characterization
    Wang, SF
    Shen, L
    Tong, YJ
    Chen, L
    Phang, IY
    Lim, PQ
    Liu, TX
    [J]. POLYMER DEGRADATION AND STABILITY, 2005, 90 (01) : 123 - 131
  • [7] Biodegradable poly(lactic acid)/chitosan-modified montmorillonite nanocomposites: Preparation and characterization
    Wu, Tzong-Ming
    Wu, Cheng-Yang
    [J]. POLYMER DEGRADATION AND STABILITY, 2006, 91 (09) : 2198 - 2204
  • [8] Synthesis and characterization of laminated hydroxyapatite/chitosan nanocomposites
    Zuo, Guifu
    Wan, Yizao
    Wang, Lei
    Liu, Chao
    He, Fang
    Luo, Honglin
    [J]. MATERIALS LETTERS, 2010, 64 (19) : 2126 - 2128