Synthesis of 2-phenyl pyridine derivatives from aryl ketones and 1,3-diaminopropane using palladium acetate as a catalyst

被引：13
作者：
Ghodse, Shrikant M. [1 ]
Telvekar, Vikas N. [1 ]
机构：
[1] Inst Chem Technol, Dept Pharmaceut Sci & Technol, Mumbai 400019, Maharashtra, India
来源：
TETRAHEDRON LETTERS | 2017年 / 58卷 / 06期
关键词：
Aryl ketone; 1,3-Diaminopropane; Phenyl pyridine; Palladium acetate; N BOND ACTIVATION; SUBSTITUIERTER PYRIDINE; 2-ARYLPYRIDINES; ACETOPHENONES; STRATEGY;
D O I：
10.1016/j.tetlet.2016.12.075
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A simple and efficient method for the synthesis of 2-phenyl pyridine via cyclization of aryl ketone with 1,3-diaminopropane using palladium acetate is established. This method is mild, operationally simple, involves short reaction time and involves easy workup procedure to afford the corresponding 2-phenyl pyridines in moderate to good yield. (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码：524 / 526
页数：3
相关论文
共 17 条
  • [1] Andrea M, 2011, EUR J ORG CHEM, V33, P6725
  • [2] The total synthesis of streptonigrin and related antitumor antibiotic natural products
    Bringmann, G
    Reichert, Y
    Kane, VV
    [J]. TETRAHEDRON, 2004, 60 (16) : 3539 - 3574
  • [3] Etoricoxib in the treatment of osteoarthritis over 52-weeks: a double-blind, active-comparator controlled trial [NCT00242489]
    Curtis, SP
    Bockow, B
    Fisher, C
    Olaleye, J
    Compton, A
    Ko, AT
    Reicin, AS
    [J]. BMC MUSCULOSKELETAL DISORDERS, 2005, 6 (1)
  • [4] Hantzsch A., 1881, BERICHTE DTSCH CHEM, V14, P1637, DOI DOI 10.1002/CBER.18810140214
  • [5] Visible light-induced aerobic C-N bond activation: a photocatalytic strategy for the preparation of 2-arylpyridines and 2-arylquinolines
    Hu, Bei
    Li, Yuyuan
    Dong, Wuheng
    Xie, Xiaomin
    Wan, Jun
    Zhang, Zhaoguo
    [J]. RSC ADVANCES, 2016, 6 (54): : 48315 - 48318
  • [6] Michael AG, 1980, J ORGANOMET CHEM, V3, P341
  • [7] Bioimaging, antibacterial and antifungal properties of imidazole-pyridine fluorophores: Synthesis, characterization and solvatochromism
    Nagarajan, N.
    Vanitha, G.
    Ananth, D. Arul
    Rameshkumar, A.
    Sivasudha, T.
    Renganathan, R.
    [J]. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 2013, 127 : 212 - 222
  • [8] Sapra S, 2016, CHEM SCI J, V7, P2
  • [9] Metal-free oxidative cyclization of acetophenones with diamines: a facile access to phenylpyridines
    Sharma, Rohit
    Patel, Neha
    Vishwakarma, Ram A.
    Bharatam, Prasad V.
    Bharate, Sandip B.
    [J]. CHEMICAL COMMUNICATIONS, 2016, 52 (05) : 1009 - 1012
  • [10] Dark-field oxidative addition-based chemosensing:: New bis-cyclometalated Pt(II) complexes and phosphorescent detection of cyanogen halides
    Thomas, Samuel W., III
    Venkatesan, Koushik
    Muller, Peter
    Swager, Timothy M.
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (51) : 16641 - 16648
12