Case-control study of hospital admission with asthma in children aged 5-14 years: relation with road traffic in north west London

被引:85
作者
Wilkinson, P
Elliott, P
Grundy, C
Shaddick, G
Thakrar, B
Walls, P
Falconer, S
机构
[1] Univ London Imperial Coll Sci Technol & Med, Dept Epidemiol & Publ Hlth, London W2 1PG, England
[2] Univ London London Sch Hyg & Trop Med, Environm Epidemiol Unit, London WC1E 7HT, England
关键词
childhood asthma; road traffic pollution;
D O I
10.1136/thx.54.12.1070
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Background-Evidence for an association between road traffic pollution and asthma is inconclusive. We report a case-control study of hospital admissions for asthma and respiratory illness among children aged 5-14 in relation to proxy markers of traffic related pollution. Methods-The study was based on routine hospital admissions data in 1992/3 and 1993/4 for North Thames (West) health region within the M25 motorway. Cases were defined as emergency admissions for asthma (n = 1380) or all respiratory illness including asthma (n = 2131), and controls (n = 5703) were other emergency admissions excluding accidents, Cases and controls were compared with respect to distance of residence hom nearest main road or roads with peak hour traffic >1000 vehicles and traffic volume within 150 m of residence, obtained by Geographical information System techniques. Statistical analysis included adjustment for age, sex, admitting hospital, and a deprivation score for the census enumeration district of residence. Results-Adjusted odds ratios of hospital admission for asthma and respiratory illness for children living within 150 m of a main road compared with those living further away were, respectively, 0.93 (95% CI 0.82 to 1.06) and 1.02 (95% CI 0.92 to 1.14). Conclusions-This study showed no association between risk of hospital admission far asthma or respiratory illness among children aged 5-14 and proxy markers of road traffic pollution.
引用
收藏
页码:1070 / 1074
页数:5
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