Taxanes of the needles of Taxus x media

The chloroform-soluble portion of the methanolic extract of the needles of Taxus x media was chromatographed on a C-18 reverse-phase column and the major components were separated by direct crystallization. Further fractionation by chromatography on normal phase silica gel, of the filtrates from the region surrounding brevifoliol, yielded two taxanes belonging to the 2(3-->20)abeo-taxane group, one of the taxicin-type, in addition to taxinine M, 10-deacetyl paclitaxel, 10-deacetyl paclitaxel-7-xyloside, 10-deacetyl paclitaxel-C-7-xyloside, apigenin and p-hydroxybenzaldehyde. Copyright (C) 1996 Elsevier Science Ltd