Biotech nanocellulose: A review on progress in product design and today's state of technical and medical applications

被引：43

作者：

Klemm, Dieter ^{[1
]}

Petzold-Welcke, Katrin ^{[1
]}

Kramer, Friederike ^{[1
,2
]}

Richter, Thomas ^{[3
,4
]}

Raddatz, Vanessa ^{[1
]}

Fried, Wolfgang ^{[1
]}

Nietzsche, Sandor ^{[5
]}

Bellmann, Tom ^{[6
]}

Fischer, Dagmar ^{[6
]}

机构：

[1] KKF Gesell, Hans Knoll Str 6, D-07745 Jena, Germany

[2] Univ Hosp Jena, Dept Orthoped, Expt Rheumatol Unit, Waldkliniken Eisenberg, Klosterlausnitzerstr 81, D-07607 Eisenberg, Germany

[3] Polymet Jena Assoc, Hans Knoll Str 6, D-07745 Jena, Germany

[4] SurA Chem, Posener Weg 2, D-07751 Bucha, Germany

[5] Univ Hosp Jena, Ctr Electron Microscopy, Ziegelmuehlenweg 1, D-07743 Jena, Germany

[6] Friedrich Schiller Univ Jena, Dept Pharmaceut Technol & Biopharm, Lessingstr 8, D-07743 Jena, Germany

来源：

CARBOHYDRATE POLYMERS | 2021年 / 254卷

关键词：

Bacterial nanocellulose; Multilayered hydrogels; Biotechnological design; Medical implants; Drug delivery; Composites; BACTERIAL CELLULOSE MEMBRANES; DRUG-DELIVERY SYSTEM; CONTROLLED-RELEASE; IN-VITRO; MECHANICAL-PROPERTIES; TRANSDERMAL DELIVERY; COMPOSITE; SURFACE; HYDROCHLORIDE; NANOPARTICLES;

D O I：

10.1016/j.carbpol.2020.117313

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Biotech nanocellulose (bacterial nanocellulose, BNC) is a high potential natural polymer. Moreover, it is the only cellulose type that can be produced biotechnologically using microorganisms resulting in hydmgels with high purity, high mechanical strength and an interconnecting micropore system. Recently, the subject of intensive research is to influence this biosynthesis to create function-determining properties. This review reports on the progress in product design and today's state of technical and medical applications. A novel, dynamic, template-based technology, called Mobile Matrix Reservoir Technology (MMR Tech), is highlighted. Thereby, shape, dimensions, surface properties, and nanonetwork structures can be designed in a process-controlled manner. The formed multilayer materials open up new applications in medicine and technology. Especially medical materials for cardiovascular and visceral surgery, and drug delivery systems are developed. The effective production of layer-structured composites and coatings are important for potential applications in the electronics, paper, food and packaging technologies.

引用

页数：16

共 112 条

[41]

Klemm D., 2016, 251 ACS NAT M EXP

[42]

Klemm D., 2013, Patent No. [UG DE102012201272B4, 102012201272]

[43] Nanocellulose as a natural source for groundbreaking applications in materials science: Today's state [J].