One-pot synthesis of tetrahydroquinolines catalyzed by Dy(OTf)3 in aqueous solution

被引：26

作者：

Chen, RF ^{[1
]}

Qian, CT ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Orgnomet Chem, Shanghai 200032, Peoples R China

来源：

SYNTHETIC COMMUNICATIONS | 2002年 / 32卷 / 16期

关键词：

tetrahydroquinolines; Dy(OTf)(3) catalyst; aqueous solution reaction;

D O I：

10.1081/SCC-120005937

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Various 4-substituted-1-methyltetrahydroquinolines are easily accessible from the one-pot condensation reaction of N-methylaniline with commercial formaldehyde solution and electron-rich alkenes in the presence of Dy(OTf)(3) (1 mol %) under mild conditions at ambient temperature and in the absence of any organic solvents.

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收藏

页码：2543 / 2548

页数：6

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