Samter's Triad: State of the Art

被引：17
作者：
Kim, Sung-Dong
Cho, Kyu-Sup [1 ]
机构：
[1] Pusan Natl Univ, Sch Med, Pusan Natl Univ Hosp, Dept Otorhinolatyngol Head & Neck Surg, 179 Gudeok Ro, Busan 49241, South Korea
来源：
CLINICAL AND EXPERIMENTAL OTORHINOLARYNGOLOGY | 2018年 / 11卷 / 02期
关键词：
Aspirin; Asthma; Nasal Polyps; Sinusitis; Desensitization; Physiopathology; EXACERBATED RESPIRATORY-DISEASE; ASPIRIN-INDUCED ASTHMA; ENDOSCOPIC SINUS SURGERY; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; CYSTEINYL LEUKOTRIENE RECEPTORS; NASAL PROVOCATION TEST; LONG-TERM TREATMENT; INTOLERANT ASTHMA; DESENSITIZATION-TREATMENT; PROMOTER POLYMORPHISM;
D O I：
10.21053/ceo.2017.01606
中图分类号：
R76 [耳鼻咽喉科学];
学科分类号：
100213 ;
摘要：
Samter's triad (ST) is a well-known disease characterized by the triad of bronchial asthma, nasal polyps, and aspirin intolerance. Over the past few years, a rapid development in the knowledge of the pathogenesis and clinical characteristics of ST has happened. The aim of this paper is to review the recent investigations on the pathophysiological mechanisms and genetic background, diagnosis, and different therapeutic options of ST to advance our understanding of the mechanism and the therapeutic control of ST. As concern for ST increase, more application of aspirin desensitization will be required to manage this disease successfully. There is also a need for continued research efforts in pathophysiology, treatment, and possible prevention.
引用
收藏
页码：71 / 80
页数：10
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