Enhancement of the perception of systemic pain in women with vulvar vestibulitis

被引:47
作者
Granot, M
Friedman, M
Yarnitsky, D
Zimmer, EZ [1 ]
机构
[1] Rambam Med Ctr, Dept Obstet & Gynecol, IL-31096 Haifa, Israel
[2] Rambam Med Ctr, Dept Neurol, IL-31096 Haifa, Israel
[3] Univ Haifa, Fac Hlth & Welfare Studies, IL-31999 Haifa, Israel
[4] Technion Israel Inst Technol, Fac Med, Haifa, Israel
关键词
D O I
10.1016/S1470-0328(02)01416-7
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective The aim of this study was to determine whether the characteristics of systemic pain perception and anxiety differ between women with vulvar vestibulitis and healthy women. Design Case control study. Setting Tertiary care hospital. Population Forty-four women with vulvar vestibulitis and 41 healthy women participated in the study. Methods First, the women's state and trait anxiety was evaluated. Thereafter, heat pain stimuli were applied to the women's forearm and the pain and unpleasantness thresholds, as well as magnitude estimation of perceived intensity and unpleasantness of suprathreshold stimuli, were assessed. Finally, blood pressure was measured before, during and after a heat stimulus of 46degreesC. Main outcome measures Pain threshold and suprathreshold, and anxiety levels of women with vulvar vestibulitis. Results Women with vulvar vestibulitis had a higher anxiety state (40.0 [12.8] vs 34.1 [10.8], P = 0.044), a higher anxiety trait (42.1 [10.2] vs 35.6 [7.5], P = 0.005), a lower pain threshold (42.2degreesC [2.5] vs 43.6degreesC [1.9], P = 0.006). a lower unpleasantness threshold (40.2degreesC [2.9] vs 41.7degreesC [2.3], P = 0.023), a higher magnitude estimation of suprathreshold pain at 47degreesC (88.3 [14.9] vs 70.8 [14.9], P = 0.0001) and at 48degreesC (96.1 [7.3] vs 84.6 [14.8], P < 0.0001), a higher scoring of tonic pain perception (65.2 [17.3] vs 53.0 [18.6], P = 0.006) and a higher increase in systolic blood pressure during tonic pain stimuli (4.6 [9.6] vs -2.1 [8.7] mmHg, P = 0.005). Conclusion Women with vulvar vestibulitis have an enhanced systemic pain perception and are more anxious.
引用
收藏
页码:863 / 866
页数:4
相关论文
共 32 条
  • [1] Baggish M S, 1995, Obstet Gynecol Surv, V50, P618, DOI 10.1097/00006254-199508000-00023
  • [2] A randomized comparison of group cognitive-behavioral therapy, surface electromyographic biofeedback, and vestibulectomy in the treatment of dyspareunia resulting from vulvar vestibulitis
    Bergeron, S
    Binik, YM
    Khalifé, S
    Pagidas, K
    Glazer, HI
    Meana, M
    Amsel, R
    [J]. PAIN, 2001, 91 (03) : 297 - 306
  • [3] Vulvar vestibulitis syndrome: A critical review
    Bergeron, S
    Binik, YM
    Khalife, S
    Pagidas, K
    [J]. CLINICAL JOURNAL OF PAIN, 1997, 13 (01) : 27 - 42
  • [4] Bornstein J, 1998, Obstet Gynecol Surv, V53, P39, DOI 10.1097/00006254-199801000-00022
  • [5] Predicting the outcome of surgical treatment of vulvar vestibulitis
    Bornstein, J
    Goldik, Z
    Stolar, Z
    Zarfati, D
    Abramovici, H
    [J]. OBSTETRICS AND GYNECOLOGY, 1997, 89 (05) : 695 - 698
  • [6] Vulvar vestibulitis: Physical or psychosexual problem?
    Bornstein, J
    Zarfati, D
    Goldik, Z
    Abramovici, H
    [J]. OBSTETRICS AND GYNECOLOGY, 1999, 93 (05) : 876 - 880
  • [7] Danielsson I, 2001, BRIT J OBSTET GYNAEC, V108, P456
  • [8] Edwards L, 1997, J REPROD MED, V42, P135
  • [9] Fields HL, 1999, PAIN, pS61, DOI 10.1016/S0304-3959(99)00139-6
  • [10] FRIEDRICH EG, 1987, J REPROD MED, V32, P110