Nordic guidelines 2014 for diagnosis and treatment of gastroenteropancreatic neuroendocrine neoplasms

被引:101
作者
Janson, Eva Tiensuu [1 ]
Sorbye, Halfdan [2 ]
Welin, Staffan [1 ]
Federspiel, Birgitte [3 ]
Gronbaek, Henning [4 ]
Hellman, Per [5 ]
Ladekarl, Morten [6 ]
Langer, Seppo W. [7 ]
Mortensen, Jann [8 ]
Schalin-Jantti, Camilla [9 ]
Sundin, Anders [10 ]
Sundlov, Anna [11 ]
Thiis-Evensen, Espen [12 ]
Knigge, Ulrich [13 ,14 ]
机构
[1] Uppsala Univ, Dept Med Sci, S-75185 Uppsala, Sweden
[2] Haukeland Hosp, Dept Oncol, N-5021 Bergen, Norway
[3] Univ Copenhagen, Rigshosp, Fac Hlth Sci, Dept Pathol, DK-2100 Copenhagen, Denmark
[4] Aarhus Univ Hosp, Dept Gastroenterol & Hepatol, DK-8000 Aarhus, Denmark
[5] Uppsala Univ, Dept Surg Sci, S-75185 Uppsala, Sweden
[6] Aarhus Univ Hosp, Dept Oncol, DK-8000 Aarhus, Denmark
[7] Univ Copenhagen, Rigshosp, Fac Hlth Sci, Dept Oncol, DK-2100 Copenhagen, Denmark
[8] Univ Copenhagen, Rigshosp, Fac Hlth Sci, Dept Clin Physiol Nucl Med & PET, DK-2100 Copenhagen, Denmark
[9] Univ Helsinki, Cent Hosp, Dept Med, Div Endocrinol, Helsinki, Finland
[10] Uppsala Univ, Dept Radiol Oncol & Radiat Sci, Uppsala, Sweden
[11] Skane Univ Hosp, Dept Oncol, Lund, Sweden
[12] Univ Oslo, Rikshosp, Oslo Univ Hosp, Dept Organ Transplantat, N-0027 Oslo, Norway
[13] Univ Copenhagen, Rigshosp, Fac Hlth Sci, Dept Surg C, DK-2100 Copenhagen, Denmark
[14] Univ Copenhagen, Rigshosp, Fac Hlth Sci, Dept Endocrinol PE, DK-2100 Copenhagen, Denmark
关键词
RADIOLABELED SOMATOSTATIN ANALOG; SMALL-CELL CARCINOMA; INTERFERON-ALPHA; CHROMOGRANIN-A; PROGNOSTIC-FACTORS; GEP-NETS; HEPATIC METASTASES; Y-90; MICROSPHERES; LIVER METASTASES; ENDOCRINE TUMORS;
D O I
10.3109/0284186X.2014.941999
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background. The diagnostic work-up and treatment of patients with neuroendocrine neoplasms (NENs) has undergone major recent advances and new methods are currently introduced into the clinic. An update of the WHO classification has resulted in a new nomenclature dividing NENs into neuroendocrine tumours (NETs) including G1 (Ki67 index <= 2%) and G2 (Ki67 index 3-20%) tumours and neuroendocrine carcinomas (NECs) with Ki67 index > 20%, G3. Aim. These Nordic guidelines summarise the Nordic Neuroendocrine Tumour Group's current view on how to diagnose and treat NEN-patients and are meant to be useful in the daily practice for clinicians handling these patients.
引用
收藏
页码:1284 / 1297
页数:14
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