Nordic guidelines 2014 for diagnosis and treatment of gastroenteropancreatic neuroendocrine neoplasms

被引:101
作者
Janson, Eva Tiensuu [1 ]
Sorbye, Halfdan [2 ]
Welin, Staffan [1 ]
Federspiel, Birgitte [3 ]
Gronbaek, Henning [4 ]
Hellman, Per [5 ]
Ladekarl, Morten [6 ]
Langer, Seppo W. [7 ]
Mortensen, Jann [8 ]
Schalin-Jantti, Camilla [9 ]
Sundin, Anders [10 ]
Sundlov, Anna [11 ]
Thiis-Evensen, Espen [12 ]
Knigge, Ulrich [13 ,14 ]
机构
[1] Uppsala Univ, Dept Med Sci, S-75185 Uppsala, Sweden
[2] Haukeland Hosp, Dept Oncol, N-5021 Bergen, Norway
[3] Univ Copenhagen, Rigshosp, Fac Hlth Sci, Dept Pathol, DK-2100 Copenhagen, Denmark
[4] Aarhus Univ Hosp, Dept Gastroenterol & Hepatol, DK-8000 Aarhus, Denmark
[5] Uppsala Univ, Dept Surg Sci, S-75185 Uppsala, Sweden
[6] Aarhus Univ Hosp, Dept Oncol, DK-8000 Aarhus, Denmark
[7] Univ Copenhagen, Rigshosp, Fac Hlth Sci, Dept Oncol, DK-2100 Copenhagen, Denmark
[8] Univ Copenhagen, Rigshosp, Fac Hlth Sci, Dept Clin Physiol Nucl Med & PET, DK-2100 Copenhagen, Denmark
[9] Univ Helsinki, Cent Hosp, Dept Med, Div Endocrinol, Helsinki, Finland
[10] Uppsala Univ, Dept Radiol Oncol & Radiat Sci, Uppsala, Sweden
[11] Skane Univ Hosp, Dept Oncol, Lund, Sweden
[12] Univ Oslo, Rikshosp, Oslo Univ Hosp, Dept Organ Transplantat, N-0027 Oslo, Norway
[13] Univ Copenhagen, Rigshosp, Fac Hlth Sci, Dept Surg C, DK-2100 Copenhagen, Denmark
[14] Univ Copenhagen, Rigshosp, Fac Hlth Sci, Dept Endocrinol PE, DK-2100 Copenhagen, Denmark
关键词
RADIOLABELED SOMATOSTATIN ANALOG; SMALL-CELL CARCINOMA; INTERFERON-ALPHA; CHROMOGRANIN-A; PROGNOSTIC-FACTORS; GEP-NETS; HEPATIC METASTASES; Y-90; MICROSPHERES; LIVER METASTASES; ENDOCRINE TUMORS;
D O I
10.3109/0284186X.2014.941999
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background. The diagnostic work-up and treatment of patients with neuroendocrine neoplasms (NENs) has undergone major recent advances and new methods are currently introduced into the clinic. An update of the WHO classification has resulted in a new nomenclature dividing NENs into neuroendocrine tumours (NETs) including G1 (Ki67 index <= 2%) and G2 (Ki67 index 3-20%) tumours and neuroendocrine carcinomas (NECs) with Ki67 index > 20%, G3. Aim. These Nordic guidelines summarise the Nordic Neuroendocrine Tumour Group's current view on how to diagnose and treat NEN-patients and are meant to be useful in the daily practice for clinicians handling these patients.
引用
收藏
页码:1284 / 1297
页数:14
相关论文
共 74 条
[41]   Epidemiology of malignant digestive neuroendocrine tumours [J].
Lepage, C. ;
Bouvier, A. M. ;
Faivre, J. .
EUROPEAN JOURNAL OF ENDOCRINOLOGY, 2013, 168 (04) :R77-R83
[42]   Hepatic Arterial Embolization versus Chemoembolization in the Treatment of Liver Metastases from Well-Differentiated Midgut Endocrine Tumors: A Prospective Randomized Study [J].
Maire, Frederique ;
Lombard-Bohas, Catherine ;
O'Toole, Dermot ;
Vullierme, Marie-Pierre ;
Rebours, Vinciane ;
Couvelard, Anne ;
Pelletier, Anne Laure ;
Zappa, Magaly ;
Pilleul, Frank ;
Hentic, Olivia ;
Hammel, Pascal ;
Ruszniewski, Philippe .
NEUROENDOCRINOLOGY, 2012, 96 (04) :294-300
[43]   Contrast-enhanced ultrasonography in evaluating hepatic metastases from neuroendocrine tumours [J].
Massironi, Sara ;
Conte, Dario ;
Sciola, Valentina ;
Pirola, Lorena ;
Paggi, Silvia ;
Fraquelli, Mirella ;
Ciafardini, Clorinda ;
Spampatti, Matilde P. ;
Peracchi, Maddalena .
DIGESTIVE AND LIVER DISEASE, 2010, 42 (09) :635-641
[44]   Malignancies of the appendix: Beyond case series reports [J].
McGory, ML ;
Maggard, MA ;
Kang, HJ ;
O'Connell, JB ;
Ko, CY .
DISEASES OF THE COLON & RECTUM, 2005, 48 (12) :2264-2271
[45]   Gastrointestinal carcinoid: epidemiological and survival evidence from a large population-based study (n=25 531) [J].
Mocellin, S. ;
Nitti, D. .
ANNALS OF ONCOLOGY, 2013, 24 (12) :3040-3044
[46]   Review article: somatostatin analogues in the treatment of gastroenteropancreatic neuroendocrine (carcinoid) tumours [J].
Modlin, I. M. ;
Pavel, M. ;
Kidd, M. ;
Gustafsson, B. I. .
ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2010, 31 (02) :169-188
[47]   STREPTOZOCIN ALONE COMPARED WITH STREPTOZOCIN PLUS FLUOROURACIL IN THE TREATMENT OF ADVANCED ISLET-CELL CARCINOMA [J].
MOERTEL, CG ;
HANLEY, JA ;
JOHNSON, LA .
NEW ENGLAND JOURNAL OF MEDICINE, 1980, 303 (21) :1189-1194
[48]   Long-Term Results of Surgery for Small Intestinal Neuroendocrine Tumors at a Tertiary Referral Center [J].
Norlen, Olov ;
Stalberg, Peter ;
Oberg, Kjell ;
Eriksson, John ;
Hedberg, Jakob ;
Hessman, Ola ;
Janson, Eva Tiensuu ;
Hellman, Per ;
Akerstrom, Goran .
WORLD JOURNAL OF SURGERY, 2012, 36 (06) :1419-1431
[49]   Prophylactic Cholecystectomy in Midgut Carcinoid Patients [J].
Norlen, Olov ;
Hessman, Ola ;
Stalberg, Peter ;
Akerstrom, Goran ;
Hellman, Per .
WORLD JOURNAL OF SURGERY, 2010, 34 (06) :1361-1367
[50]   Biotherapies for GEP-NETs [J].
Oberg, Kjell .
BEST PRACTICE & RESEARCH CLINICAL GASTROENTEROLOGY, 2012, 26 (06) :833-841