Visualization of Orbital Involvement of Erdheim-Chester Disease on PET/CT

被引:3
作者
Beylergil, Volkan [1 ]
Carrasquillo, Jorge A. [1 ,2 ]
Hyman, David M. [3 ]
Diamond, Eli L. [4 ]
机构
[1] Mem Sloan Kettering Canc Ctr, Dept Radiol, Mol & Imaging Therapy Serv, New York, NY 10065 USA
[2] Weill Cornell Med Ctr, Dept Radiol, New York, NY USA
[3] Mem Sloan Kettering Canc Ctr, Dev Therapeut Unit, New York, NY 10065 USA
[4] Mem Sloan Kettering Canc Ctr, Dept Neurol, New York, NY 10065 USA
关键词
Erdheim-Chester; FDG; PET/CT; eye; orbital; non-Langerhans; LANGERHANS CELL HISTIOCYTOSIS; FDG PET/CT; TOMOGRAPHY; MUTATION;
D O I
10.1097/RLU.0000000000000452
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
We report a 58-year-old man who presented with swelling and redness in his left eye, headache, and blurred vision. A contrast-enhanced CT of the orbits revealed bilateral orbital masses. Whole-body PET/CT showed bilateral retrobulbar hypermetabolic soft tissue lesions, multiple areas of soft tissue involvement, and osseous lesions in bilateral lower extremities. An open surgical biopsy of the left orbital mass revealed xanthomatous non-Langerhans histiocytic infiltrate with Touton giant cells, positive for CD68 but negative for CD1a, establishing a diagnosis of Erdheim-Chester disease. © 2014 by Lippincott Williams & Wilkins.
引用
收藏
页码:660 / 661
页数:2
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