Ureteral small cell carcinoma

被引：13

作者：

Kuroda, Naoto ^{[1
]}

Katto, Kazunobu ^{[2
]}

Tamura, Masato ^{[2
]}

Shiotsu, Tomoyuki ^{[2
]}

Inoue, Kaori ^{[1
]}

Ohara, Masahiko ^{[1
]}

Mizuno, Keiko ^{[1
]}

Lee, Gang-Hong ^{[3
]}

机构：

[1] Kochi Red Cross Hosp, Dept Diagnost Pathol, Kochi 7808562, Japan

[2] Kochi Red Cross Hosp, Dept Urol, Kochi 7808562, Japan

[3] Kochi Univ, Kochi Med Sch, Dept Pathol, Kochi 780, Japan

来源：

MEDICAL MOLECULAR MORPHOLOGY | 2009年 / 42卷 / 01期

关键词：

Ureter; Small cell carcinoma; Immunohistochemistry; RENAL PELVIS; SQUAMOUS-CELL;

D O I：

10.1007/s00795-007-0384-5

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Ureteral small cell carcinoma is very rare; only eight cases have been reported in the literature. In this article, we report the ninth case of ureteral small cell carcinoma. A 79-year-old Japanese man presented with asymptomatic macrohematuria, and left nephroureterectomy was performed. The nonpapillary and broad-based tumor, which measured 3.7 x 3.7 x 2.0 cm, was seen in the lower portion of the left ureter just above the ureteral orifice. Microscopically, the tumor was composed of urothelial carcinoma and small cell carcinoma. Immunohistochemically, neoplastic cells of small cell carcinoma were focally positive for chromogranin A. In the normal ureteral mucosa adjacent to the tumor, some endocrine cells positive for chromogranin A and synaptophysin were identified. In conclusion, we suggest that endocrine cells in the ureteral urothelial epithelium may be precursor cells of ureteral small cell carcinoma.

引用

页码：55 / 57

页数：3

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