Administration of Brincidofovir and Convalescent Plasma in a Patient With Ebola Virus Disease

被引:69
作者
Florescu, Diana F. [1 ,2 ]
Kalil, Andre C. [1 ]
Hewlett, Angela L. [1 ]
Schuh, Amy J. [3 ,4 ]
Stroher, Ute [3 ,4 ]
Uyeki, Timothy M. [5 ]
Smith, Philip W. [1 ]
机构
[1] Univ Nebraska, Med Ctr, Div Infect Dis, Omaha, NE 68182 USA
[2] Univ Nebraska, Med Ctr, Transplant Surg Program, Omaha, NE 68182 USA
[3] Ctr Dis Control & Prevent, Viral Special Pathogens Branch, Div High Consequence Pathogens, Atlanta, GA USA
[4] Ctr Dis Control & Prevent, Pathol Natl Ctr Emerging & Zoonot, Atlanta, GA USA
[5] Ctr Dis Control & Prevent, Influenza Div, Natl Ctr Immunizat & Resp Dis, Atlanta, GA USA
关键词
Ebola; investigational therapies; trials; HUMORAL IMMUNE-RESPONSE; HEMORRHAGIC-FEVER; CMX001; SUDAN; INFECTIONS; OUTBREAK; GULU;
D O I
10.1093/cid/civ395
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
From 2014 to May 2015, >26 000 Ebola virus disease (EVD) cases were reported from West Africa. We present a patient with EVD who received brincidofovir and convalescent plasma. The relative contributions of supportive care, investigational therapies, and patient's immune-response on survival could not be determined. Randomized trials are needed.
引用
收藏
页码:969 / 973
页数:5
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