Corneal wound healing following laser in situ keratomileusis (LASIK): a histopathological study in rabbits

被引：53

作者：

Kato, T ^{[1
]}

Nakayasu, K ^{[1
]}

Hosoda, Y ^{[1
]}

Watanabe, Y ^{[1
]}

Kanai, A ^{[1
]}

机构：

[1] Juntendo Univ, Sch Med, Dept Ophthalmol, Bunkyo Ku, Tokyo 1138421, Japan

来源：

BRITISH JOURNAL OF OPHTHALMOLOGY | 1999年 / 83卷 / 11期

关键词：

D O I：

10.1136/bjo.83.11.1302

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Aims-To investigate the histopathological changes of rabbit corneas after laser in situ keratomileusis (LASIK) and to evaluate the corneal wound healing process. Methods-A LASIK was performed on white rabbit eyes. Postoperatively, rabbits were killed on days 1 and 7, and at 1, 3, and 9 months. Results-Periodic acid Schiff (PAS) positive material and disorganised collagen fibre were seen along the interface of the corneal flap even 9 months after operation. Conclusions-The wound healing process still continued at 9 months after LASIK indicating that a much longer time than expected was required for corneal wound healing following LASIK.

引用

页码：1302 / 1305

页数：4

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