Three-component synthesis of novel spirooxindole-furan derivatives using pyridinium salts

被引:13
作者
Baharfar, Robabeh [1 ]
Asghari, Sakineh [1 ]
Zaheri, Farya [1 ]
Shariati, Narges [1 ]
机构
[1] Univ Mazandaran, Dept Chem, POB 47415, Babol Sar, Iran
关键词
Spirooxindole; Interrupted Feist-Benary reaction; Isatin; 1,3-dicarbonyl compounds; Pyridinium salts;
D O I
10.1016/j.crci.2016.07.001
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A simple and efficient synthesis of novel spirooxindole-furan derivatives has been investigated by a modified version of the "interrupted" Feist-Benary (IFB) reaction of isatin derivatives, 1,3-dicarbonyl compounds and N-phenacyl pyridinium salts in the presence of triethylamine. The reaction has been carried out under mild conditions in ethanol, and the products were obtained in good to moderate yields with a simple work-up procedure. (C) 2016 Academie des sciences. Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:359 / 364
页数:6
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