Colorimetric SNP analysis using oligonucleotide-modified nanoparticles

被引:15
|
作者
Ihara, T [1 ]
Chikaura, Y [1 ]
Tanaka, S [1 ]
Jyo, A [1 ]
机构
[1] Kumamoto Univ, Fac Engn, Dept Appl Chem & Biochem, Kumamoto 8608555, Japan
关键词
D O I
10.1039/b206158a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A point mutation in the p53 gene has been detected by means of fluorescence microscopy and fluorescent resonance energy transfer (FRET) through sequence selective aggregation of DNA-modified nanoparticles, in which fluorescent dyes were impregnated.
引用
收藏
页码:2152 / 2153
页数:2
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