Expression of the Orphan Nuclear Receptor NR4A in a Putative Adenohypophyseal Homologue of Amphioxus

被引：4

作者：

Candiani, Simona ^{[1
]}

Moronti, Luca ^{[1
]}

Pestarino, Mario ^{[1
]}

机构：

[1] Univ Genoa, Dept Biol, I-16132 Genoa, Italy

来源：

TRENDS IN COMPARATIVE ENDOCRINOLOGY AND NEUROBIOLOGY | 2009年 / 1163卷

关键词：

amphioxus; nuclear orphan receptor; NR4A; developmental expression; pituitary; evolution; NGFI-B; NURR1; SYSTEM;

D O I：

10.1111/j.1749-6632.2008.03648.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Nur77, Nurr1, and NOR-1 form a subfamily (the NR4A/Nur subfamily) of transcription factors belonging to the family of nuclear receptors. In this report, we characterized the single member of such a subfamily in the amphioxus Branchiostoma floridae. Developmental expression analysis of AmphiNR4A showed transcripts limited to the putative adenohypophyseal homologue of amphioxus.

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页码：361 / 364

页数：4

相关论文

共 14 条

[1] AmphiD1/β, a dopamine D1/β-adrenergic receptor from the amphioxus Branchiostoma floridae:: evolutionary aspects of the catecholaminergic system during development [J].

Candiani, S ;

Oliveri, D ;

Parodi, M ;

Castagnola, P ;

Pestarino, M .

DEVELOPMENT GENES AND EVOLUTION, 2005, 215 (12) :631-638

[2] Expression of the amphioxus Pit-1 gene (AmphiPOU1F1/Pit-1) exclusively in the developing preoral organ, a putative homolog of the vertebrate adenohypophysis [J].

Candiani, Simona ;

Holland, Nicholas D. ;

Oliveri, Diana ;

Parodi, Manuela ;

Pestarino, Mario .

BRAIN RESEARCH BULLETIN, 2008, 75 (2-4) :324-330

[3] Parkinson's disease: Mechanisms and models [J].

Dauer, W ;

Przedborski, S .

NEURON, 2003, 39 (06) :889-909

[4] Expression and function of nr4a2, lmx1b, and pitx3 in zebrafish dopaminergic and noradrenergic neuronal development [J].

Filippi, Alida ;

Duerr, Katrin ;

Ryu, Soojin ;

Willaredt, Marc ;

Holzschuh, Jochen ;

Driever, Wolfgang .

BMC DEVELOPMENTAL BIOLOGY, 2007, 7

[5] Structural basis for the cell-specific activities of the NGFI-B and the Nurr1 ligand-binding domain [J].

Flaig, R ;

Greschik, H ;

Peluso-Iltis, C ;

Moras, D .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (19) :19250-19258

[6] The amphioxus genome illuminates vertebrate origins and cephalochordate biology [J].

Holland, Linda Z. ;

Albalat, Ricard ;

Azumi, Kaoru ;

Benito-Gutierrez, Elia ;

Blow, Matthew J. ;

Bronner-Fraser, Marianne ;

Brunet, Frederic ;

Butts, Thomas ;

Candiani, Simona ;

Dishaw, Larry J. ;

Ferrier, David E. K. ;

Garcia-Fernandez, Jordi ;

Gibson-Brown, Jeremy J. ;

Gissi, Carmela ;

Godzik, Adam ;

Hallbook, Finn ;

Hirose, Dan ;

Hosomichi, Kazuyoshi ;

Ikuta, Tetsuro ;

Inoko, Hidetoshi ;

Kasahara, Masanori ;

Kasamatsu, Jun ;

Kawashima, Takeshi ;

Kimura, Ayuko ;

Kobayashi, Masaaki ;

Kozmik, Zbynek ;

Kubokawa, Kaoru ;

Laudet, Vincent ;

Litman, Gary W. ;

McHardy, Alice C. ;

Meulemans, Daniel ;

Nonaka, Masaru ;

Olinski, Robert P. ;

Pancer, Zeev ;

Pennacchio, Len A. ;

Pestarino, Mario ;

Rast, Jonathan P. ;

Rigoutsos, Isidore ;

Robinson-Rechavi, Marc ;

Roch, Graeme ;

Saiga, Hidetoshi ;

Sasakura, Yasunori ;

Satake, Masanobu ;

Satou, Yutaka ;

Schubert, Michael ;

Sherwood, Nancy ;

Shiina, Takashi ;

Takatori, Naohito ;

Tello, Javier ;

Vopalensky, Pavel .

GENOME RESEARCH, 2008, 18 (07) :1100-1111

[7] The role of Nurr1 in the development of dopaminergic neurons and Parkinson's disease [J].

Jankovic, J ;

Chen, S ;

Le, WD .

PROGRESS IN NEUROBIOLOGY, 2005, 77 (1-2) :128-138

[8] Differential regulation of the transcriptional activity of the orphan nuclear receptor NGFI-B by membrane depolarization and nerve growth factor [J].

Katagiri, Y ;

Hirata, Y ;

Milbrandt, J ;

Guroff, G .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (50) :31278-31284

[9]

Laudet VGH., 2002, NUCL RECEPTOR FACTBO

[10] Neuroendocrine regulation of the hypothalamic pituitary adrenal axis by the nurr1/nur77 subfamily of nuclear receptors [J].

Murphy, EP ;

Conneely, OM .

MOLECULAR ENDOCRINOLOGY, 1997, 11 (01) :39-47