ISOLATION OF MEDICINE-APPLICABLE ACTINIUM-225 FROM THORIUM TARGETS IRRADIATED BY MEDIUM-ENERGY PROTONS

被引：57

作者：

Aliev, R. A. ^{[1
]}

Ermolaev, S. V. ^{[2
]}

Vasiliev, A. N. ^{[1
]}

Ostapenko, V. S. ^{[1
]}

Lapshina, E. V. ^{[2
]}

Zhuikov, B. L. ^{[2
]}

Zakharov, N. V. ^{[3
]}

Pozdeev, V. V. ^{[3
]}

Kokhanyuk, V. M. ^{[2
]}

Myasoedov, B. F. ^{[4
]}

Kalmykov, S. N. ^{[1
,4
]}

机构：

[1] Moscow MV Lomonosov State Univ, Moscow 119991, Russia

[2] Russian Acad Sci, Inst Nucl Res, Moscow 117312, Russia

[3] Karpov Inst Phys Chem, Obninsk Branch, Obninsk, Russia

[4] Russian Acad Sci, Frumkin Inst Phys Chem & Electrochem, Moscow, Russia

来源：

SOLVENT EXTRACTION AND ION EXCHANGE | 2014年 / 32卷 / 05期

基金：

俄罗斯基础研究基金会;

关键词：

Ac-225; proton irradiation; thorium target; actinium isolation; extraction chromatography; AC-225; THERAPY; RA-223; TH-229;

D O I：

10.1080/07366299.2014.896582

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A method of isolation of actinium-225 for nuclear medical applications from thorium targets irradiated by protons is presented. It comprises liquid extraction and extraction chromatography separations. The method demonstrates high (> 85%) chemical yield and radionuclide purity of the final product. An impurity of Ac-227 (0.1% at the end of bombardment) does not hinder Ac-225 from being used for medical Ac-225/Bi-213 generators.

引用

页码：468 / 477

页数：10

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