Response to Bcma CAR-T Cells Correlates with Pretreatment Target Antigen Density and Is Improved By Small Molecule Inhibition of Gamma Secretase

被引：20
|
作者：
Green, Damian J. [1 ,2 ]
Pont, Margot [2 ]
Cowan, Andrew J. [2 ,3 ]
Cole, Gabriel O. [2 ]
Sather, Blythe Duke [4 ]
Nagengast, Anne M. [5 ]
Song, Xaoling [5 ]
Thomas, Sushma [5 ]
Wood, Brent L. [6 ]
Blake, Michelle L. [7 ]
Works, Melissa G. [7 ]
Gooley, Ted A. [2 ]
Maloney, David G. [5 ]
Riddell, Stanley R. [2 ]
机构：
[1] Seattle Canc Care Alliance, Seattle, WA USA
[2] Fred Hutchinson Canc Res Ctr, Div Clin Res, 1124 Columbia St, Seattle, WA 98104 USA
[3] Univ Washington, Dept Med, Seattle, WA USA
[4] Lyell Immunopharma, Seattle, WA USA
[5] Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 USA
[6] Univ Washington, Dept Lab Med, Seattle, WA 98195 USA
[7] Juno Therapeut, Seattle, WA USA
来源：
BLOOD | 2019年 / 134卷
关键词：
D O I：
10.1182/blood-2019-129582
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
1856
引用
收藏
页数：3
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