Bioelectrochemistry for sensing amino acids, peptides, proteins and DNA interactions

被引:35
|
作者
Oliveira-Brett, Ana Maria [1 ]
Diculescu, Victor Constatin [1 ]
Enache, Teodor Adrian [1 ]
Fernandes, Isabel P. G. [1 ]
Chiorcea-Paquim, Ana-Maria [1 ]
Oliveira, S. Carlos B. [1 ]
机构
[1] Univ Coimbra, Dept Chem, Fac Sci & Technol, P-3004535 Coimbra, Portugal
关键词
Oxidative damage; Peptides; Proteins; DNA; Electrochemistry; GLUTATHIONE-S-TRANSFERASE; ANTICANCER ANTIBODY RITUXIMAB; BORON-DOPED DIAMOND; ELECTROCHEMICAL OXIDATION; IN-SITU; ALZHEIMERS-DISEASE; MICROCYSTIN-LR; ADSORPTION; ELECTRODES; TRYPTOPHAN;
D O I
10.1016/j.coelec.2019.03.008
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Oxidative damage to peptides, proteins and DNA is considered to be one of the major causes of cancer and age-related diseases. The interaction of biomolecules, peptides, proteins, nucleic acids and pharmaceuticals with solid electrode surfaces is not only a fundamental phenomenon but also a key to important and novel analytical sensing applications in biosensors, biotechnology, medical devices and drug-delivery schemes. Electrochemical methods can provide insight into the redox mechanisms and the electron-transfer reactions of a variety of fundamental biological processes.
引用
收藏
页码:173 / 179
页数:7
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