Anchoring Transitions of Liquid Crystals for Optical Amplification of Phospholipid Oxidation Inhibition by Ascorbic Acid

被引：3

作者：

Zhang, Minmin ^{[1
]}

Jang, Chang-Hyun ^{[1
]}

机构：

[1] Gachon Univ, Dept Chem, Seongnam Si 461701, Gyeonggi Do, South Korea

来源：

ANALYTICAL SCIENCES | 2015年 / 31卷 / 12期

基金：

新加坡国家研究基金会;

关键词：

Ascorbic acid; antioxidant; phospholipids; liquid crystals; anchoring transition; HYDROGEN-PEROXIDE; CELLS;

D O I：

10.2116/analsci.31.1329

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

There is considerable evidence that the antioxidant property of ascorbic acid (AH) is effective for reducing oxidative stress of phospholipids. Herein, a liquid crystals (LCs)-based method was developed for the optical amplification of resistance to phospholipid oxidation by AH. Phospholipid peroxidation initiated by free radicals was monitored from a homeotropic-to-planar anchoring transition of LCs via polarized optical microscopy. Alternatively, consistent homeotropic anchoring of LCs was observed when the oxidation caused by free radicals was blocked by AH.

引用

页码：1329 / 1333

页数：5

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