Hemofiltration in sepsis: where do we go from here?

被引:11
作者
Kellum, JA
Bellomo, R
机构
[1] Univ Pittsburgh, Med Ctr, Div Crit Care Med, Dept Anesthesiol & Crit Care Med, Pittsburgh, PA 15213 USA
[2] Univ Pittsburgh, Med Ctr, Dept Med, Pittsburgh, PA USA
[3] Austin & Repatriat Med Ctr, Dept Intens Care, Heidelberg, Vic, Australia
来源
CRITICAL CARE | 2000年 / 4卷 / 02期
关键词
continuous venovenous hemodialysis; continuous venovenous hemofiltration; hemofiltration; multiple-organ failure; sepsis; systemic inflammatory response syndrome;
D O I
10.1186/cc659
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Hemofiltration as an adjunct to therapy for sepsis is now 10 years old. Despite early successes and significant theoretical advantages, the treatment remains experimental. Although feasibility has been established, efficacy has proved to be much more difficult. Clinical as well as technical difficulties remain important considerations to future studies. These issues are discussed and the brief history of hemofiltration in sepsis is reviewed.
引用
收藏
页码:69 / 71
页数:3
相关论文
共 18 条
  • [1] Management of acute renal failure: New perspectives
    Alkhunaizi, AM
    Schrier, RW
    [J]. AMERICAN JOURNAL OF KIDNEY DISEASES, 1996, 28 (03) : 315 - 328
  • [2] Bellomo R, 1995, New Horiz, V3, P732
  • [3] Bellomo R, 1998, KIDNEY INT, V53, pS182
  • [4] CONTINUOUS VENOVENOUS HEMOFILTRATION WITH DIALYSIS REMOVES CYTOKINES FROM THE CIRCULATION OF SEPTIC PATIENTS
    BELLOMO, R
    TIPPING, P
    BOYCE, N
    [J]. CRITICAL CARE MEDICINE, 1993, 21 (04) : 522 - 526
  • [5] BELLOMO R, 2000, IN PRESS AM J RESP C
  • [6] Expression of adhesion molecules and activation markers on lymphocytes and monocytes during hemodialysis
    Braun, N
    [J]. BLOOD PURIFICATION, 1997, 15 (02) : 61 - 76
  • [7] Treatment of septic shock with the tumor necrosis factor receptor:Fc fusion protein
    Fisher, CJ
    Agosti, JM
    Opal, SM
    Lowry, SF
    Balk, RA
    Sadoff, JC
    Abraham, E
    Schein, RMH
    Benjamin, E
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1996, 334 (26) : 1697 - 1702
  • [8] INFUSION OF ULTRAFILTRATE FROM ENDOTOXEMIC PIGS DEPRESSES MYOCARDIAL PERFORMANCE IN NORMAL PIGS
    GROOTENDORST, AF
    VANBOMMEL, EFH
    VANLEENGOED, LAMG
    VANZANTEN, ARH
    HUIPEN, HJC
    GROENEVELD, ABJ
    [J]. JOURNAL OF CRITICAL CARE, 1993, 8 (03) : 161 - 169
  • [9] HIGH-VOLUME HEMOFILTRATION IMPROVES RIGHT VENTRICULAR-FUNCTION IN ENDOTOXIN-INDUCED SHOCK IN THE PIG
    GROOTENDORST, AF
    VANBOMMEL, EFH
    VANDERHOVEN, B
    VANLEENGOED, LAMG
    VANOSTA, ALM
    [J]. INTENSIVE CARE MEDICINE, 1992, 18 (04) : 235 - 240
  • [10] Kellum J A, 1999, Minerva Anestesiol, V65, P410