Long-term outcomes and five-year recurrence-free survival curves after native-tissue prolapse repair

被引:10
作者
Deo, Giuseppe [1 ]
Bernasconi, Davide P. [1 ]
Cola, Alice [1 ,2 ]
Palmieri, Stefania [1 ,2 ]
Spelzini, Federico [3 ]
Milani, Rodolfo [2 ]
Manodoro, Stefano [3 ]
Frigerio, Matteo [1 ,2 ]
机构
[1] Univ Milano Bicocca, Sch Med, Milan, Italy
[2] San Gerardo Hosp, ASST Monza, Dept Gynecol, Monza, Italy
[3] Infermi Hosp, AUSL Romagna, Dept Gynecol, Rimini, Italy
关键词
Long-term follow-up; Native-tissue repair; Prolapse surgery; Recurrence; Risk factors; Uterosacral ligament suspension; PELVIC ORGAN PROLAPSE; QUALITY-OF-LIFE; UTEROSACRAL LIGAMENT HYSTEROPEXY; MODIFIED MCCALL CULDOPLASTY; RISK-FACTORS; SHULL SUSPENSION;
D O I
10.1002/ijgo.12938
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective To evaluate the long-term objective and subjective outcomes to build recurrence-free survival curves after mesh-free uterosacral ligament suspension and to evaluate the long-term impact of prognostic factors on outcome measures. Methods A retrospective study analyzed 5-year follow-up after repair of primary prolapse through high uterosacral ligament suspension. Bulging symptoms and post-operative prolapse stage II or above were considered subjective and objective recurrences, respectively. The cumulative proportion of relapse-free patients in time was analyzed by Kaplan-Meier curves. Results A total of 353 women were analyzed. Five-year recurrence rates were 15.0% for objective recurrence, 13.0% for subjective recurrence, and 4.0% for the combined objective and subjective recurrences. Premenopausal status was shown to be a risk factor for anatomic (P=0.022), symptomatic (P=0.001), and combined (P=0.047) recurrence. Conversely, anterior repair was shown to be a protective factor for symptomatic (P=0.012) and combined (P=0.002) recurrence. Most of the recurrences occurred within 2 years after surgery. Conclusion Long-term outcomes after high uterosacral ligament suspension were satisfactory. Premenopausal status and lack of anterior repair represented risk factors for recurrence in the long term.
引用
收藏
页码:238 / 245
页数:8
相关论文
共 23 条
  • [1] The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction
    Bump, RC
    Mattiasson, A
    Bo, K
    Brubaker, LP
    DeLancey, JOL
    Klarskov, P
    Shull, BL
    Smith, ARB
    [J]. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1996, 175 (01) : 10 - 17
  • [2] Analysis of risk factors associated with surgical failure of sacrospinous suspension for uterine or vaginal vault prolapse
    Chen, Huey-Yi
    Chiu, Tsan-Hung
    Ho, Ming
    Hung, Yao-Ching
    [J]. INTERNATIONAL UROGYNECOLOGY JOURNAL, 2009, 20 (04) : 387 - 391
  • [3] Risk factors for the recurrence of pelvic organ prolapse after vaginal surgery: a review at 5 years after surgery
    Diez-Itza, I.
    Aizpitarte, I.
    Becerro, A.
    [J]. INTERNATIONAL UROGYNECOLOGY JOURNAL, 2007, 18 (11) : 1317 - 1324
  • [4] Validation of an Italian version of the prolapse quality of life questionnaire
    Digesu, GA
    Santamato, S
    Khullar, V
    Santillo, V
    Digesu, A
    Cormio, G
    Loverro, G
    Selvaggi, L
    [J]. EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2003, 106 (02): : 184 - 192
  • [5] Long-term outcomes of modified high uterosacral ligament vault suspension (HUSLS) at vaginal hysterectomy
    Doumouchtsis, Stergios K.
    Khunda, Azar
    Jeffery, Stephen T.
    Franco, Anna Virginia M.
    Fynes, Michelle M.
    [J]. INTERNATIONAL UROGYNECOLOGY JOURNAL, 2011, 22 (05) : 577 - 584
  • [6] Duan L, 2017, Zhonghua Fu Chan Ke Za Zhi, V52, P363, DOI 10.3760/cma.j.issn.0529-567X.2017.06.002
  • [7] An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint report on the terminology for female pelvic organ prolapse (POP) (vol 27, pg 165, 2016)
    Haylen, Bernard T.
    Maher, Christopher F.
    Barber, Matthew D.
    Camargo, Sergio
    Dandolu, Vani
    Digesu, Alex
    Goldman, Howard B.
    Huser, Martin
    Milani, Alfredo L.
    Moran, Paul A.
    Schaer, Gabriel. N.
    Withagen, Mariella I. J.
    [J]. INTERNATIONAL UROGYNECOLOGY JOURNAL, 2016, 27 (04) : 655 - 684
  • [8] Risk factors for recurrence after hysterectomy plus native-tissue repair as primary treatment for genital prolapse
    Manodoro, Stefano
    Frigerio, Matteo
    Cola, Alice
    Spelzini, Federico
    Milani, Rodolfo
    [J]. INTERNATIONAL UROGYNECOLOGY JOURNAL, 2018, 29 (01) : 145 - 151
  • [9] Tips and tricks for uterosacral ligament suspension: how to avoid ureteral injury
    Manodoro, Stefano
    Frigerio, Matteo
    Milani, Rodolfo
    Spelzini, Federico
    [J]. INTERNATIONAL UROGYNECOLOGY JOURNAL, 2018, 29 (01) : 161 - 163
  • [10] Manodoro S, 2017, MINERVA GINECOL, V69, P233, DOI 10.23736/S0026-4784.16.03977-0