Synthesis and evaluation of antifungal activity of naphthoquinone derivatives

被引：36
作者：
Errante, Giaccomo
La Motta, Grazia
Lagana, Catarina
Wittebolle, Vierle
Sarciron, Marie-Elisabeth
Barret, Roland
机构：
[1] Univ Lyon 1, Chim Therapeut Lab, Fac Pharm, F-69373 Lyon 08, France
[2] Univ Lyon 1, Parasitol Lab, Fac Pharm, EA 3741, F-69373 Lyon, France
来源：
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | 2006年 / 41卷 / 06期
关键词：
naphthoquinone derivative; amino-sulfinylnaphthoquinone; 2-phenylsulfinyl-3-arylthio-1,4-dihydronaphtalenes; antifungal activity;
D O I：
10.1016/j.ejmech.2006.02.003
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
3-Arylamino-2-phenylsulfinylnaphthoquinones, 2,3-diarylthio-naphthoquinones and 2-phenylsulfinyl-3-arylthio-1,4-dihydronaphtalenes are synthesized and tested against five fungi. The activities of these products were better than amphotericine B against all the strains except for Candida albicans. (c) 2006 Elsevier SAS. All rights reserved.
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收藏
页码：773 / 778
页数：6
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