Sorafenib Use in Hepatocellular Carcinoma: More Questions Than Answers

被引：27

作者：

Abou-Alfa, Ghassan K. ^{[1
,2
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, Dept Internal Med, New York, NY 10065 USA

[2] Weill Cornell Med Coll, Dept Internal Med, New York, NY USA

来源：

HEPATOLOGY | 2014年 / 60卷 / 01期

关键词：

RENAL-CELL CARCINOMA; PHASE-II; SOLID TUMORS; MODIFIED RECIST; THERAPY; BRIVANIB; BAY-43-9006; MECHANISMS; GROWTH; CANCER;

D O I：

10.1002/hep.27044

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

[No abstract available]

引用

页码：15 / 18

页数：4

共 24 条

[1] Phase II study of sorafenib in patients with advanced hepatocellular carcinoma [J].

Abou-Alfa, Ghassan K. ;

Schwartz, Lawrence ;

Ricci, Sergio ;

Amadori, Dino ;

Santoro, Armando ;

Figer, Arie ;

De Greve, Jacques ;

Douillard, Jean-Yves ;

Lathia, Chetan ;

Schwartz, Brian ;

Taylor, Ian ;

Moscovici, Marius ;

Saltz, Leonard B. .

JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (26) :4293-4300

[2]

Abou-Alfa Ghassan K, 2011, Gastrointest Cancer Res, V4, P40

[3] A Phase II Trial of Intrapatient Dose-Escalated Sorafenib in Patients With Metastatic Renal Cell Carcinoma [J].

Amato, Robert ;

Zhai, Jim ;

Willis, James ;

Saxena, Somyata ;

Defoe, Melissa .

CLINICAL GENITOURINARY CANCER, 2012, 10 (03) :153-158

[4] Comparison of tumor response by Response Evaluation Criteria in Solid Tumors (RECIST) and modified RECIST in patients treated with sorafenib for hepatocellular carcinoma [J].

Edeline, Julien ;

Boucher, Eveline ;

Rolland, Yan ;

Vauleon, Elodie ;

Pracht, Marc ;

Perrin, Christophe ;

Le Roux, Catherine ;

Raoul, Jean-Luc .

CANCER, 2012, 118 (01) :147-156

[5] VEGF-targeted therapy: mechanisms of anti-tumour activity [J].

Ellis, Lee M. ;

Hicklin, Daniel J. .

NATURE REVIEWS CANCER, 2008, 8 (08) :579-591

[6] Phase II, Open-Label Study of Brivanib as Second-Line Therapy in Patients with Advanced Hepatocellular Carcinoma [J].

Finn, Richard S. ;

Kang, Yoon-Koo ;

Mulcahy, Mary ;

Polite, Blase N. ;

Lim, Ho Yeong ;

Walters, Ian ;

Baudelet, Christine ;

Manekas, Demetrios ;

Park, Joong-Won .

CLINICAL CANCER RESEARCH, 2012, 18 (07) :2090-2098

[7] RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth [J].

Hatzivassiliou, Georgia ;

Song, Kyung ;

Yen, Ivana ;

Brandhuber, Barbara J. ;

Anderson, Daniel J. ;

Alvarado, Ryan ;

Ludlam, Mary J. C. ;

Stokoe, David ;

Gloor, Susan L. ;

Vigers, Guy ;

Morales, Tony ;

Aliagas, Ignacio ;

Liu, Bonnie ;

Sideris, Steve ;

Hoeflich, Klaus P. ;

Jaiswal, Bijay S. ;

Seshagiri, Somasekar ;

Koeppen, Hartmut ;

Belvin, Marcia ;

Friedman, Lori S. ;

Malek, Shiva .

NATURE, 2010, 464 (7287) :431-U132

[8] Field-Practice Study of Sorafenib Therapy for Hepatocellular Carcinoma: A Prospective Multicenter Study in Italy [J].

Iavarone, Massimo ;

Cabibbo, Giuseppe ;

Piscaglia, Fabio ;

Zavaglia, Claudio ;

Grieco, Antonio ;

Villa, Erica ;

Camma, Calogero ;

Colombo, Massimo ;

Sangiovanni, Angelo ;

Vavassori, Sara ;

Romeo, Raffaella ;

Di Marco, Vito ;

Craxi, Antonio ;

Borghi, Alberto ;

Granito, Alessandro ;

Bolondi, Luigi ;

Airoldi, Aldo ;

Pinzello, Giovambattista ;

Biolato, Marco ;

Racco, Simona ;

Pompili, Maurizio ;

Lei, Barbara ;

De Maria, Nicola .

HEPATOLOGY, 2011, 54 (06) :2055-2063

[9] Brivanib Versus Sorafenib As First-Line Therapy in Patients With Unresectable, Advanced Hepatocellular Carcinoma: Results From the Randomized Phase III BRISK-FL Study [J].

Johnson, Philip J. ;

Qin, Shukui ;

Park, Joong-Won ;

Poon, Ronnie T. P. ;

Raoul, Jean-Luc ;

Philip, Philip A. ;

Hsu, Chih-Hung ;

Hu, Tsung-Hui ;

Heo, Jeong ;

Xu, Jianming ;

Lu, Ligong ;

Chao, Yee ;

Boucher, Eveline ;

Han, Kwang-Hyub ;

Paik, Seung-Woon ;

Robles-Avina, Jorge ;

Kudo, Masatoshi ;

Yan, Lunan ;

Sobhonslidsuk, Abhasnee ;

Komov, Dmitry ;

Decaens, Thomas ;

Tak, Won-Young ;

Jeng, Long-Bin ;

Liu, David ;

Ezzeddine, Rana ;

Walters, Ian ;

Cheng, Ann-Lii .

JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (28) :3517-+

[10] Genetic predisposition of hand-foot skin reaction after sorafenib therapy in patients with hepatocellular carcinoma [J].

Lee, Joo Ho ;

Chung, Young-Hwa ;

Kim, Jeong A. ;

Shim, Ju Hyun ;

Lee, Danbi ;

Lee, Han Chu ;

Shin, Eun-Soon ;

Yoon, Jung Hwan ;

Kim, Byung Ik ;

Bae, Si Hyun ;

Koh, Kwang Cheol ;

Park, Neung-Hwa .

CANCER, 2013, 119 (01) :136-142

← 1 2 3 →