Are there proliferating neuronal precursors in adult rat dorsal root ganglia?

被引：33
作者：
Ciaroni, S [1 ]
Cecchini, T
Cuppini, R
Ferri, P
Ambrogini, P
Bruno, C
Del Grande, P
机构：
[1] Univ Urbino, Inst Morphol Sci, I-61029 Urbino, Italy
[2] Univ Urbino, Inst Physiol Sci, I-61029 Urbino, Italy
来源：
NEUROSCIENCE LETTERS | 2000年 / 281卷 / 01期
关键词：
postnatal neurogenesis; dorsal root ganglia; proliferation; differentiation; tocopherols; 5-bromo-2-deoxyuridine;
D O I：
10.1016/S0304-3940(00)00785-0
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The origin of new neurons in dorsal root ganglia of adult rat was investigated using an experimental model in which postnatal neurogenesis naturally occurring is enhanced and restricted in a brief period of life. Possible mitotic origin of new neurons was investigated by means of 5-bromo-2-deoxyuridine, anti-NF 200 antibody was used to detect if proliferated cells showed a neuronal phenotype. The results suggest that postnatal neurogenesis in dorsal root ganglia could depend only in part on precursor proliferation and that normally new neurons derive from the late differentiation of postmitotic cells. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码：69 / 71
页数：3
相关论文
共 50 条
[31]   Baikal Skullcap Extract Stimulates Neurite Growth in Cultures of Rat Dorsal Root Ganglia [J].
A. Ya. Shurygin ;
N. V. Bezzubov ;
E. A. Ignatova ;
S. M. Nikolaev ;
I. V. Viktorov .
Bulletin of Experimental Biology and Medicine, 2002, 134 :47-49
[32]   Rat dorsal root ganglia express distinctive forms of the α2 calcium channel subunit [J].
Luo, ZD .
NEUROREPORT, 2000, 11 (16) :3449-3452
[33]   Baikal skullcap extract stimulates neurite growth in cultures of rat dorsal root ganglia [J].
Shurygin, AY ;
Bezzubov, NV ;
Ignatova, EA ;
Nikolaev, SM ;
Viktorov, IV .
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2002, 134 (01) :47-49
[34]   Effect of colchicine on neuropeptide Y expression in rat dorsal root ganglia and spinal cord [J].
Cougnon-Aptel, N ;
Whiteside, GT ;
Munglani, R .
NEUROSCIENCE LETTERS, 1999, 259 (01) :45-48
[35]   The effects of lead on transient outward currents of acutely dissociated rat dorsal root ganglia [J].
Dai, XQ ;
Ruan, DY ;
Chen, JT ;
Wang, M ;
Cai, L .
BRAIN RESEARCH, 2001, 904 (02) :327-340
[36]   Substrate Availability of Mutant SPT Alters Neuronal Branching and Growth Cone Dynamics in Dorsal Root Ganglia [J].
Jun, Byung Kyu ;
Chandra, Ankush ;
Kuljis, Dika ;
Schmidt, Brian P. ;
Eichler, Florian S. .
JOURNAL OF NEUROSCIENCE, 2015, 35 (40) :13713-13719
[37]   An Intimate Role for Adult Dorsal Root Ganglia Resident Cycling Cells in the Generation of Local Macrophages and Satellite Glial Cells [J].
Krishnan, Anand ;
Bhavanam, Sudha ;
Zochodne, Douglas .
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2018, 77 (10) :929-941
[38]   Caspase-Mediated Apoptosis in Sensory Neurons of Cultured Dorsal Root Ganglia in Adult Mouse [J].
Momeni, Hamid Reza ;
Mehranjani, Malek Soleimani ;
Shariatzadeh, Mohammad Ali ;
Haddadi, Mahnaz .
CELL JOURNAL, 2013, 15 (03) :212-217
[39]   DISTRIBUTION OF PROTEIN GENE-PRODUCT-9.5 (PGP-9.5) IMMUNOREACTIVITY IN THE DORSAL-ROOT GANGLIA OF ADULT-RAT [J].
CALZADA, B ;
NAVES, FJ ;
DELVALLE, ME ;
VEGA, JA .
ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER, 1994, 176 (05) :437-441
[40]   Role of a voltage-sensitive calcium channel blocker on inhibition of apoptosis in sensory neurons of cultured dorsal root ganglia in adult rat [J].
Momeni, Hamid Reza ;
Shariatzadeh, Mohammad Ali ;
Hamta, Ahmad ;
Mirfakhraei, Maryam ;
Eskandari, Najmeh .
PHYSIOLOGY AND PHARMACOLOGY, 2013, 17 (01) :51-59
12345