The use of telomerized cells for tissue engineering

被引：52
作者：
Shay, JW
Wright, WE
机构：
[1] Univ Texas, SW Med Ctr, Dept Cell Biol, Dallas, TX 75390 USA
[2] Ellison Med Fdn, Bethesda, MD USA
来源：
NATURE BIOTECHNOLOGY | 2000年 / 18卷 / 01期
关键词：
D O I：
10.1038/71872
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
引用
收藏
页码：22 / 23
页数：2
相关论文
共 8 条
[1]   Extension of life-span by introduction of telomerase into normal human cells [J].
Bodnar, AG ;
Ouellette, M ;
Frolkis, M ;
Holt, SE ;
Chiu, CP ;
Morin, GB ;
Harley, CB ;
Shay, JW ;
Lichtsteiner, S ;
Wright, WE .
SCIENCE, 1998, 279 (5349) :349-352
[2]   Creation of human tumour cells with defined genetic elements [J].
Hahn, WC ;
Counter, CM ;
Lundberg, AS ;
Beijersbergen, RL ;
Brooks, MW ;
Weinberg, RA .
NATURE, 1999, 400 (6743) :464-468
[3]   Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype [J].
Jiang, XR ;
Jimenez, G ;
Chang, E ;
Frolkis, M ;
Kusler, B ;
Sage, M ;
Beeche, M ;
Bodnar, AG ;
Wahl, GM ;
Tlsty, TD ;
Chiu, CP .
NATURE GENETICS, 1999, 21 (01) :111-114
[4]   SPECIFIC ASSOCIATION OF HUMAN TELOMERASE ACTIVITY WITH IMMORTAL CELLS AND CANCER [J].
KIM, NW ;
PIATYSZEK, MA ;
PROWSE, KR ;
HARLEY, CB ;
WEST, MD ;
HO, PLC ;
COVIELLO, GM ;
WRIGHT, WE ;
WEINRICH, SL ;
SHAY, JW .
SCIENCE, 1994, 266 (5193) :2011-2015
[5]   Absence of cancer-associated changes in human fibroblasts immortalized with telomerase [J].
Morales, CP ;
Holt, SE ;
Ouellette, M ;
Kaur, KJ ;
Yan, Y ;
Wilson, KS ;
White, MA ;
Wright, WE ;
Shay, JW .
NATURE GENETICS, 1999, 21 (01) :115-118
[6]   Tissue engineering [J].
Persidis, A .
NATURE BIOTECHNOLOGY, 1999, 17 (05) :508-510
[7]   Formation of functional tissue from transplanted adrenocortical cells expressing telomerase reverse transcriptase [J].
Thomas, M ;
Yang, LQ ;
Hornsby, PJ .
NATURE BIOTECHNOLOGY, 2000, 18 (01) :39-42
[8]   Adrenocortical tissue formed by transplantation of normal clones of bovine adrenocortical cells in scid mice replaces the essential functions of the animals' adrenal glands [J].
Thomas, M ;
Northrup, SR ;
Hornsby, PJ .
NATURE MEDICINE, 1997, 3 (09) :978-983
1