Recent Advances of Magnetic Nanomaterials in Bone Tissue Repair

被引：49
作者：
Fan, Daoyang [1 ]
Wang, Qi [2 ]
Zhu, Tengjiao [3 ]
Wang, Hufei [4 ,5 ]
Liu, Bingchuan [3 ]
Wang, Yifan [6 ]
Liu, Zhongjun [3 ]
Liu, Xunyong [7 ]
Fan, Dongwei [2 ]
Wang, Xing [4 ,5 ]
机构：
[1] Zhengzhou Univ, Affiliated Hosp 1, Dept Orthoped, Zhengzhou, Peoples R China
[2] Peking Univ Third Hosp, Dept Pediat, Beijing, Peoples R China
[3] Peking Univ Third Hosp, Dept Orthoped, Beijing, Peoples R China
[4] Chinese Acad Sci, Inst Chem, State Key Lab Polymer Phys & Chem, Beijing Natl Lab Mol Sci, Beijing, Peoples R China
[5] Univ Chinese Acad Sci, Beijing, Peoples R China
[6] N Carolina State Univ, CED Educ, Raleigh, NC 27695 USA
[7] Ludong Univ, Sch Chem & Mat Sci, Yantai, Peoples R China
来源：
FRONTIERS IN CHEMISTRY | 2020年 / 8卷
基金：
中国国家自然科学基金;
关键词：
magnetic nanomaterials; bone tissue repair; magnetic field; magnetic particles; stem cells; tissue engineering scaffolds; MESENCHYMAL STEM-CELLS; POT MULTICOMPONENT SYNTHESIS; OSTEOGENIC DIFFERENTIATION; DRUG-DELIVERY; COMPOSITE SCAFFOLD; NANOPARTICLES; FIELD; NANOCOMPOSITE; EFFICIENT; SILICA;
D O I：
10.3389/fchem.2020.00745
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The magnetic field has been proven to enhance bone tissue repair by affecting cell metabolic behavior. Magnetic nanoparticles are used as biomaterials due to their unique magnetic properties and good biocompatibility. Through endocytosis, entering the cell makes it easier to affect the physiological function of the cell. Once the magnetic particles are exposed to an external magnetic field, they will be rapidly magnetized. The magnetic particles and the magnetic field work together to enhance the effectiveness of their bone tissue repair treatment. This article reviews the common synthesis methods, the mechanism, and application of magnetic nanomaterials in the field of bone tissue repair.
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页数：15
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