Convergent synthetic studies towards the ribosyl-diazepanone core of the liposidomycins

被引：12

作者：

Bourdreux, Yann ^{[1
]}

Drouillat, Bruno ^{[1
]}

Greck, Christine ^{[1
]}

机构：

[1] Univ Versailles, Inst Lavoisier Versailles, CNRS, UMR 8180, F-78035 Versailles, France

来源：

LETTERS IN ORGANIC CHEMISTRY | 2006年 / 3卷 / 05期

关键词：

antibiotic; diazepanone; lactamisation; liposidomycin; ribosylamino acid;

D O I：

10.2174/157017806776611827

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New types of ribosyl-diazepanone derivatives of nucleoside antibiotic liposidomycins, 12a and 12b, have been synthesised. The ribosyl 7-membered heterocycles were formed by reductive amination of the -ribosylamino acid 9 derived from D-ribose and the amino aldehydes 10a or 10b, followed by a peptidic coupling reaction.

引用

页码：368 / 370

页数：3

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