Cross-colonization of infants with probiotic organisms in a neonatal unit

被引：25
作者：
Hickey, L. [1 ,2 ,3 ]
Garland, S. M. [4 ,5 ,6 ,7 ]
Jacobs, S. E. [3 ,5 ,7 ,8 ]
O'Donnell, C. P. F. [2 ,9 ]
Tabrizi, S. N. [4 ,5 ,6 ,7 ]
机构：
[1] Royal Childrens Hosp, Dept Neonatal Med, Parkville, Vic 3052, Australia
[2] Natl Univ Ireland Univ Coll Dublin, Sch Med & Med Sci, Dublin, Ireland
[3] Royal Childrens Hosp, Neonatal Serv, Parkville, Vic 3052, Australia
[4] Royal Childrens Hosp, Womens Ctr Infect Dis, Parkville, Vic 3052, Australia
[5] Univ Melbourne, Dept Obstet & Gynaecol, Parkville, Vic 3052, Australia
[6] Royal Childrens Hosp, Dept Microbiol, Parkville, Vic 3052, Australia
[7] Royal Childrens Hosp, Infect & Immun Grp, Murdoch Childrens Res Inst, Parkville, Vic 3052, Australia
[8] Royal Childrens Hosp, Neonatal Res Grp, Murdoch Childrens Res Inst, Parkville, Vic 3052, Australia
[9] Natl Matern Hosp, Dublin 2, Ireland
来源：
JOURNAL OF HOSPITAL INFECTION | 2014年 / 88卷 / 04期
基金：
英国医学研究理事会;
关键词：
Cross-colonization; Neonatal unit; Preterm infants; Probiotics; RANDOMIZED CONTROLLED-TRIAL; LATE-ONSET SEPSIS; PRETERM INFANTS;
D O I：
10.1016/j.jhin.2014.09.006
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
This study aimed to assess probiotic cross-colonization between infants in a neonatal unit where probiotics were being administered to preterm infants during a clinical trial. We tested stool samples from all infants present in the unit at two time points; the first was during the trial and the second was after trial completion. Samples from 43 infants were tested during the trial; all five infants receiving probiotics and three of 38 not receiving probiotics were colonized. Only one of 44 infants tested after the trial was colonized. The rate of cross-colonization was lower than in previous probiotic studies. (C) 2014 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码：226 / 229
页数：4
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