Combined Loss of Tet1 and Tet2 Promotes B-Cell, but Not Myeloid Malignancies in Mice

被引:0
|
作者
Zhao, Zhigang [1 ,2 ,3 ]
Li, Lin [4 ]
Dawlaty, Meelad [5 ]
Pan, Feng [1 ,3 ]
Li, Zhe [3 ]
Zhou, Yuan [6 ,7 ,8 ]
Shi, Hui [6 ,7 ,8 ,9 ]
Chen, Shi [10 ,11 ]
Weeks, Ophelia [12 ]
Yuan, Weiping [6 ,8 ,13 ]
Ni, Hongyu [14 ]
Yang, Feng-Chun [3 ,10 ,11 ]
Jaenisch, Rudolph [5 ]
Jin, Peng [4 ]
Xu, Mingjiang [1 ,3 ]
机构
[1] Univ Miami, Dept Biochem & Mol Biol, Sylvester Canc Ctr, Miami, FL 33101 USA
[2] Tianjin Med Univ, Dept Hematol & Oncol, Canc Inst & Hosp, Tianjin, Peoples R China
[3] Indiana Univ Sch Med, Dept Pediat, Herman B Wells Ctr Pediat Res, Indianapolis, IN 46202 USA
[4] Emory Univ, Sch Med, Dept Human Genet, Atlanda, GA USA
[5] MIT, Whitehead Inst Biomed Res, Dept Biol, Cambridge, MA USA
[6] Chinese Acad Med Sci, Inst Hematol, State Key Lab Expt Hematol, Tianjin, Peoples R China
[7] Chinese Acad Med Sci, Blood Dis Hosp, Ctr Stem Cell Med, Tianjin, Peoples R China
[8] Peking Union Med Coll, Tianjin, Peoples R China
[9] Univ Miami, Leonard M Miller Sch Med, Miami, FL 33136 USA
[10] Univ Miami, Leonard M Miller Sch Med, Dept Biochem & Mol Biol, Miami, FL 33136 USA
[11] Univ Miami, Leonard M Miller Sch Med, Sylvester Comprehens Canc Ctr, Miami, FL 33136 USA
[12] Florida Int Univ, Dept Biol Sci, Miami, FL 33199 USA
[13] Chinese Acad Med Sci, Blood Dis Hosp, Tianjin, Peoples R China
[14] Univ Illinois, Dept Pathol, Chicago, IL USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice
    Zhao, Zhigang
    Chen, Li
    Dawlaty, Meelad M.
    Pan, Feng
    Weeks, Ophelia
    Zhou, Yuan
    Cao, Zeng
    Shi, Hui
    Wang, Jiapeng
    Lin, Li
    Chen, Shi
    Yuan, Weiping
    Qin, Zhaohui
    Ni, Hongyu
    Nimer, Stephen D.
    Yang, Feng-Chun
    Jaenisch, Rudolf
    Jin, Peng
    Xu, Mingjiang
    CELL REPORTS, 2015, 13 (08): : 1692 - 1704
  • [2] Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies
    Abdel-Wahab, Omar
    Mullally, Ann
    Hedvat, Cyrus
    Garcia-Manero, Guillermo
    Patel, Jay
    Wadleigh, Martha
    Malinge, Sebastien
    Yao, JinJuan
    Kilpivaara, Outi
    Bhat, Rukhmi
    Huberman, Kety
    Thomas, Sabrena
    Dolgalev, Igor
    Heguy, Adriana
    Paietta, Elisabeth
    Le Beau, Michelle M.
    Beran, Miloslav
    Tallman, Martin S.
    Ebert, Benjamin L.
    Kantarjian, Hagop M.
    Stone, Richard M.
    Gilliland, D. Gary
    Crispino, John D.
    Levine, Ross L.
    BLOOD, 2009, 114 (01) : 144 - 147
  • [3] TET2 mutations in myelodysplasia and myeloid malignancies
    Mullighan, Charles G.
    NATURE GENETICS, 2009, 41 (07) : 766 - 767
  • [4] TET2 mutations in myelodysplasia and myeloid malignancies
    Charles G Mullighan
    Nature Genetics, 2009, 41 : 766 - 767
  • [5] Specific functions of TET1 and TET2 in regulating mesenchymal cell lineage determination
    Cakouros, Dimitrios
    Hemming, Sarah
    Gronthos, Kahlia
    Liu, Renjing
    Zannettino, Andrew
    Shi, Songtao
    Gronthos, Stan
    EPIGENETICS & CHROMATIN, 2019, 12 (1)
  • [6] Combined Deficiency of Tet1 and Tet2 Causes Epigenetic Abnormalities but Is Compatible with Postnatal Development
    Dawlaty, Meelad M.
    Breiling, Achim
    Le, Thuc
    Raddatz, Guenter
    Barrasa, M. Inmaculada
    Cheng, Albert W.
    Gao, Qing
    Powell, Benjamin E.
    Li, Zhe
    Xu, Mingjiang
    Faull, Kym F.
    Lyko, Frank
    Jaenisch, Rudolf
    DEVELOPMENTAL CELL, 2013, 24 (03) : 310 - 323
  • [7] Specific functions of TET1 and TET2 in regulating mesenchymal cell lineage determination
    Dimitrios Cakouros
    Sarah Hemming
    Kahlia Gronthos
    Renjing Liu
    Andrew Zannettino
    Songtao Shi
    Stan Gronthos
    Epigenetics & Chromatin, 12
  • [8] Endogenous epitope-tagging of Tet1, Tet2 and Tet3 identifies TET2 as a naive pluripotency marker
    Pantier, Raphael
    Tatar, Tulin
    Colby, Douglas
    Chambers, Ian
    LIFE SCIENCE ALLIANCE, 2019, 2 (05)
  • [9] TET2 mutations in Diffuse Large B-Cell Lymphoma: The Role of TET2 in the Regulation of Methylation Patterns at TET2 Target Genes
    Asmar, Fazila
    Christensen, Jesper
    Johansen, Jens V.
    Blabjerg, Anders
    Pedersen, Anja
    Hother, Christoffer
    Ralfkiaer, Ulrik
    Helin, Kristian
    Gronbaek, Kirsten
    BLOOD, 2011, 118 (21) : 598 - 599
  • [10] Familial myeloid malignancies with germline TET2 mutation
    Nicolas Duployez
    Laure Goursaud
    Laurène Fenwarth
    Claire Bories
    Alice Marceau-Renaut
    Thomas Boyer
    Elise Fournier
    Olivier Nibourel
    Catherine Roche-Lestienne
    Guillemette Huet
    David Beauvais
    Céline Berthon
    Nathalie Cambier
    Bruno Quesnel
    Claude Preudhomme
    Leukemia, 2020, 34 : 1450 - 1453