The isoflavonoid genistein induces apoptosis by activation of caspase-3 and inhibits metastatitic tumor growth in vivo.

被引:0
|
作者
Buechler, P [1 ]
Hines, OJ [1 ]
Gukovskaya, AS [1 ]
Mouria, M [1 ]
Pandol, SJ [1 ]
Reber, HA [1 ]
机构
[1] Univ Calif Los Angeles, Sch Med, Los Angeles, CA USA
关键词
D O I
10.1016/S0016-5085(00)80387-X
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
5267
引用
收藏
页码:A1143 / A1143
页数:1
相关论文
共 50 条
  • [41] Hypertonic shock inhibits growth factor receptor signaling, induces caspase-3 activation, and causes reversible fragmentation of the mitochondrial network
    Copp, J
    Wiley, S
    Ward, MW
    van der Geer, P
    AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2005, 288 (02): : C403 - C415
  • [42] siRNA targeting midkine inhibits gastric cancer cells growth and induces apoptosis involved caspase-3,8,9 activation and mitochondrial depolarization
    Wang, Qingling
    Huang, Yahong
    Ni, Yanhong
    Wang, Hui
    Hou, Yayi
    JOURNAL OF BIOMEDICAL SCIENCE, 2007, 14 (06) : 783 - 795
  • [43] α-Mangostin inhibits the growth and induces apoptosis of human ovarian carcinoma, PA-1 cells through cell cycle arrest, ROS generation and Caspase-3 activation
    Jafri, A.
    Rais, J.
    Siddiqui, S.
    Kumar, S.
    Arshad, M.
    CANCER MEDICINE, 2018, 7 : 30 - 30
  • [44] Small interference RNA targeting heat-shock protein 27 inhibits the growth of prostatic cell lines and induces apoptosis via caspase-3 activation in vitro
    Rocchi, Palma
    Jugpal, Paul
    So, Alan
    Sinneman, Shannon
    Ettinger, Susan
    Fazli, Ladan
    Nelson, Colleen
    Gleave, Martin
    BJU INTERNATIONAL, 2006, 98 (05) : 1082 - 1089
  • [45] Caspase-3 protease activation during the process of genistein-induced apoptosis in TM4 testicular cells
    Kumi-Diaka, J
    Butler, A
    BIOLOGY OF THE CELL, 2000, 92 (02) : 115 - 124
  • [46] Hydrogen peroxide inhibits activation, not activity, of cellular caspase-3
    Shacter, E
    Lee, YJ
    FREE RADICAL BIOLOGY AND MEDICINE, 1999, 27 : S109 - S109
  • [47] MDMA induces caspase-3 activation in the limbic system but not in striatum
    Tamburini, Ilaria
    Blandini, Fabio
    Gesi, Marco
    Frenzilli, Giada
    Nigro, Marco
    Giusiani, Mario
    Paparelli, Antonio
    Fornai, Francesco
    CELLULAR AND MOLECULAR MECHANISMS OF DRUGS OF ABUSE AND NEUROTOXICITY: COCAINE, GHB, AND SUBSTITUTED AMPHETAMINES, 2006, 1074 : 377 - 381
  • [48] Pentylenetetrazole kindling induces activation of caspase-3 in the rat brain
    Pavlova T.V.
    Yakovlev A.A.
    Stepanichev M.Y.
    Mendzheritskii A.M.
    Gulyaeva N.V.
    Neuroscience and Behavioral Physiology, 2004, 34 (1) : 45 - 47
  • [49] Pentylenetetrazole kindling induces caspase-3 activation in rat brain
    Pavlova, TV
    Yakovlev, AA
    Stepanichev, MY
    Mendzheritsky, AM
    Gulyaeva, NV
    ZHURNAL VYSSHEI NERVNOI DEYATELNOSTI IMENI I P PAVLOVA, 2003, 53 (01) : 110 - 112
  • [50] Irisin Induces Apoptosis in Metastatic Prostate Cancer Cells and Inhibits Tumor Growth In Vivo
    Alshanqiti, Khalil H.
    Alomar, Sumayyah F.
    Alzoman, Nourah
    Almomen, Aliyah
    CANCERS, 2023, 15 (15)