The isoflavonoid genistein induces apoptosis by activation of caspase-3 and inhibits metastatitic tumor growth in vivo.

被引：0
|
作者：
Buechler, P [1 ]
Hines, OJ [1 ]
Gukovskaya, AS [1 ]
Mouria, M [1 ]
Pandol, SJ [1 ]
Reber, HA [1 ]
机构：
[1] Univ Calif Los Angeles, Sch Med, Los Angeles, CA USA
来源：
GASTROENTEROLOGY | 2000年 / 118卷 / 04期
关键词：
D O I：
10.1016/S0016-5085(00)80387-X
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
5267
引用
收藏
页码：A1143 / A1143
页数：1
相关论文
共 50 条
  • [31] Phyllanthus amarus Inhibits Cell Growth and Induces Apoptosis in Dalton's Lymphoma Ascites Cells Through Activation of Caspase-3 and Downregulation of Bcl-2
    Harikumar, Kuzhuvelil B.
    Kuttan, Girija
    Kuttan, Ramadasan
    INTEGRATIVE CANCER THERAPIES, 2009, 8 (02) : 190 - 194
  • [32] Prevention of metastatic pancreatic cancer growth in vivo by induction of apoptosis with genistein, a naturally occurring isoflavonoid
    Büchler, P
    Gukovskaya, TS
    Mouria, T
    Büchler, MC
    Büchler, MW
    Friess, H
    Pandol, TJ
    Reber, HA
    Hines, OJ
    PANCREAS, 2003, 26 (03) : 264 - 273
  • [33] TGF-β1 inhibits caspase-3 activation and neuronal apoptosis in rat hippocampal cultures
    Zhu, Y
    Ahlemeyer, B
    Bauerbach, E
    Krieglstein, J
    NEUROCHEMISTRY INTERNATIONAL, 2001, 38 (03) : 227 - 235
  • [34] Adenosine triphosphate induces activation of caspase-3 in apoptosis of human granulosa-luteal cells
    Tai, CJ
    Chang, SJ
    Chien, LY
    Leung, PCK
    Tzeng, CR
    ENDOCRINE JOURNAL, 2005, 52 (03) : 327 - 335
  • [35] The cytoprotective agent, amifostine, induces apoptosis and activation of caspase-3 in chronic lymphocytic leukemia.
    Lagneaux, L
    Delforge, A
    Dejeneffe, M
    Massy, M
    Bernier, M
    Bron, D
    BLOOD, 2001, 98 (11) : 283B - 283B
  • [36] Peroxynitrite induces apoptosis of HL-60 cells by activation of a caspase-3 family protease
    Lin, KT
    Xue, JY
    Lin, MC
    Spokas, EG
    Sun, FF
    Wong, PYK
    AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 1998, 274 (04): : C855 - C860
  • [37] Fluoride induces apoptosis by caspase-3 activation in human leukemia HL-60 cells
    C.D. Anuradha
    S. Kanno
    S. Hirano
    Archives of Toxicology, 2000, 74 : 226 - 230
  • [38] Amrubicin induces apoptosis in human tumor cells mediated by the activation of caspase-3/7 preceding a loss of mitochondrial membrane potential
    Hanada, Mitsuharu
    Noguchi, Toshihiro
    Yamaoka, Takashi
    CANCER SCIENCE, 2006, 97 (12) : 1396 - 1403
  • [39] 4-hydroxynonenal induces apoptosis via caspase-3 activation and cytochrome c release
    Ji, C
    Amarnath, V
    Pietenpol, JA
    Marnett, LJ
    CHEMICAL RESEARCH IN TOXICOLOGY, 2001, 14 (08) : 1090 - 1096
  • [40] Sulindac induces apoptosis, inhibits proliferation and activates caspase-3 in Hep G2 cells
    Liu, JJ
    Wang, JY
    Hertervig, E
    Nilsson, Å
    Duan, RD
    ANTICANCER RESEARCH, 2002, 22 (1A) : 263 - 266
12345