The Nuts and Bolts of Food Immunotherapy: The Future of Food Allergy

被引：12

作者：

Anvari, Sara ^{[1
,2
]}

Anagnostou, Katherine ^{[1
,2
]}

机构：

[1] Texas Childrens Hosp, Dept Pediat, Sect Immunol Allergy & Rheumatol, Houston, TX 77030 USA

[2] Baylor Coll Med, Dept Pediat, Sect Immunol Allergy & Rheumatol, Houston, TX 77030 USA

来源：

CHILDREN-BASEL | 2018年 / 5卷 / 04期

关键词：

food allergy; desensitization; oral immunotherapy; sublingual immunotherapy; epicutaneous immunotherapy; children; PEANUT ORAL IMMUNOTHERAPY; COWS MILK ALLERGY; TERM-FOLLOW-UP; DOUBLE-BLIND; SUBLINGUAL IMMUNOTHERAPY; NATURAL-HISTORY; EOSINOPHILIC ESOPHAGITIS; EPICUTANEOUS IMMUNOTHERAPY; EGG ALLERGY; KIWI FRUIT;

D O I：

10.3390/children5040047

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Food allergies are on the rise and have a major impact on the quality of life of the food allergic child and their family. Currently, the mainstream treatment for food allergies is strict avoidance and elimination of the allergenic food(s) from the patient's diet in order to prevent an allergic reaction. However, recent advances in research have presented new therapeutic options for food allergic patients that are potentially becoming promising alternatives to traditional treatment. Food immunotherapy is the most popular of these new emerging interventions and has been studied intensively over the last decade for various foods. In this review, we discuss this exciting new development that is aspiring to become part of the mainstream therapy for food allergy.

引用

页数：9

共 62 条

[1] Efficacy and safety of high-dose peanut oral immunotherapy with factors predicting outcome [J].

Anagnostou, K. ;

Clark, A. ;

King, Y. ;

Islam, S. ;

Deighton, J. ;

Ewan, P. .

CLINICAL AND EXPERIMENTAL ALLERGY, 2011, 41 (09) :1273-1281

[2] Assessing the efficacy of oral immunotherapy for the desensitisation of peanut allergy in children (STOP II): a phase 2 randomised controlled trial [J].

Anagnostou, Katherine ;

Islam, Sabita ;

King, Yvonne ;

Foley, Loraine ;

Pasea, Laura ;

Bond, Simon ;

Palmer, Chris ;

Deighton, John ;

Ewan, Pamela ;

Clark, Andrew .

LANCET, 2014, 383 (9925) :1297-1304

[3] Guidelines for the Diagnosis and Management of Food Allergy in the United States: Report of the NIAID-Sponsored Expert Panel [J].

不详 .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2010, 126 (06) :S5-S58

[4] Phase 1 results of safety and tolerability in a rush oral immunotherapy protocol to multiple foods using Omalizumab [J].

Begin, Philippe ;

Dominguez, Tina ;

Wilson, Shruti P. ;

Bacal, Liane ;

Mehrotra, Anjuli ;

Kausch, Bethany ;

Trela, Anthony ;

Tavassoli, Morvarid ;

Hoyte, Elisabeth ;

O'Riordan, Gerri ;

Blakemore, Alanna ;

Seki, Scott ;

Hamilton, Robert G. ;

Nadeau, Kari C. .

ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY, 2014, 10

[5] Efficacy and Safety of AR101 in Oral Immunotherapy for Peanut Allergy: Results of ARC001, a Randomized, Double-Blind, Placebo-Controlled Phase 2 Clinical Trial [J].

Bird, J. Andrew ;

Spergel, Jonathan M. ;

Jones, Stacie M. ;

Rachid, Rima ;

Assa'ad, Amal H. ;

Wang, Julie ;

Leonard, Stephanie A. ;

Laubach, Susan S. ;

Kim, Edwin H. ;

Vickery, Brian P. ;

Davis, Benjamin P. ;

Heimall, Jennifer ;

Cianferoni, Antonella ;

MacGinnitie, Andrew J. ;

Crestani, Elena ;

Burks, A. Wesley .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2018, 6 (02) :476-+

[6] Oral peanut immunotherapy in children with peanut anaphylaxis [J].

Blumchen, Katharina ;

Ulbricht, Helen ;

Staden, Ute ;

Dobberstein, Kerstin ;

Beschorner, John ;

de Oliveira, Lucila Camargo Lopes ;

Shreffler, Wayne G. ;

Sampson, Hugh A. ;

Niggemann, Bodo ;

Wahn, Ulrich ;

Beyer, Kirsten .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2010, 126 (01) :83-91

[7] Prediction of tolerance on the basis of quantification of egg white-specific IgE antibodies in children with egg allergy [J].

Boyano-Martínez, T ;

García-Ara, C ;

Díaz-Pena, JM ;

Martín-Esteban, M .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2002, 110 (02) :304-309

[8] Egg oral immunotherapy in nonanaphylactic children with egg allergy [J].

Buchanan, Ariana D. ;

Green, Todd D. ;

Jones, Stacie M. ;

Scurlock, Amy M. ;

Christie, Lynn ;

Althage, Karen A. ;

Steele, Pamela H. ;

Pons, Laurent ;

Heim, Rick M. ;

Lee, Laurie A. ;

Burks, A. Wesley .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2007, 119 (01) :199-205

[9] Sublingual immunotherapy for peanut allergy: Long-term follow-up of a randomized multicenter trial [J].

Burks, A. Wesley ;

Wood, Robert A. ;

Jones, Stacie M. ;

Sicherer, Scott H. ;

Fleischer, David M. ;

Scurlock, Amy M. ;

Vickery, Brian P. ;

Liu, Andrew H. ;

Henning, Alice K. ;

Lindblad, Robert ;

Dawson, Peter ;

Plaut, Marshall ;

Sampson, Hugh A. .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2015, 135 (05) :1240-U648

[10] Oral Immunotherapy for Treatment of Egg Allergy in Children [J].

Burks, A. Wesley ;

Jones, Stacie M. ;

Wood, Robert A. ;

Fleischer, David M. ;

Sicherer, Scott H. ;

Lindblad, Robert W. ;

Stablein, Donald ;

Henning, Alice K. ;

Vickery, Brian P. ;

Liu, Andrew H. ;

Scurlock, Amy M. ;

Shreffler, Wayne G. ;

Plaut, Marshall ;

Sampson, Hugh A. .

NEW ENGLAND JOURNAL OF MEDICINE, 2012, 367 (03) :233-243

← 1 2 3 4 5 6 7 →